A patch resonator for sensing blood glucose changes

In this paper, a patch resonator is presented that operates in the Industrial, Scientific, Medical (ISM) band at 2.45-2.48 GHz, when placed on a four-layered (skin, fast, blood, and muscle) tissue. The patch resonator was simulated on a square digital phantom and, for a more realistic scenario, on the digital human phantom `Hugo'. To ensure that the resonator is in contact with the voxelized model, a superstrate with the permittivity and conductivity of skin was placed on top of the resonator. The relative permittivity of the blood tissue was decreased and the input impedance matching of the resonator monitored for each case. The results show that the resonator input impedance is sensitive to the changes in the blood tissue of a realistic human model. The fields around the resonator were also simulated.

[1]  B. R. Jean,et al.  A microwave frequency sensor for non-invasive blood-glucose measurement , 2008, 2008 IEEE Sensors Applications Symposium.

[2]  T. Fujii,et al.  Integrated Broadband Microwave and Microfluidic Sensor Dedicated to Bioengineering , 2009, IEEE Transactions on Microwave Theory and Techniques.

[3]  Jayanti Venkataraman,et al.  Feasibility study for non-invasive blood glucose monitoring , 2010, 2010 IEEE Antennas and Propagation Society International Symposium.

[4]  Tutku Karacolak,et al.  Glucose-dependent dielectric properties of blood plasma , 2011, 2011 XXXth URSI General Assembly and Scientific Symposium.

[5]  R. W. Lau,et al.  The dielectric properties of biological tissues: II. Measurements in the frequency range 10 Hz to 20 GHz. , 1996, Physics in medicine and biology.

[6]  Y. Hao,et al.  Patch resonator for non-invasive detection of dielectric property changes in biological tissues , 2012, Proceedings of the 2012 IEEE International Symposium on Antennas and Propagation.

[7]  Kamal Sarabandi,et al.  Microstrip ring resonator for soil moisture measurements , 1997, IEEE Trans. Geosci. Remote. Sens..

[8]  Yang Hao,et al.  Wearable wireless sensors for healthcare applications , 2013, 2013 International Workshop on Antenna Technology (iWAT).

[9]  R. W. Lau,et al.  The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues. , 1996, Physics in medicine and biology.

[10]  W. Marsden I and J , 2012 .