Dipipanone Hydrochloride as an Adjunct to Anaesthesia in Obstetrics and Surgery

transient epithelitis, which subsided within the next weeks. No evidence of more severe tissue reaction was observed. None of the patients treated experienced radiation sickness characterized by the symptoms of lassitude, anorexia, nausea, or vomiting. We know that the number of patients studied is not large enough or the time of observation long enough for conclusive evaluation of this method of treatment. However, we feel that the results to date are encouraging. Complete regression of the'tumour was accomplished in cases of really superficial lesions. It is realized that any anatomical classification based on cystoscopic findings is subject to error. None the less, we believe that when the clinical findings are favourable this therapy should be considered as a primary measure. Summary Intracavitary instillation of colloidal radioactive gold (""Au) was used for treatment of patients with multiple papillomata of the bladder. Approximately 300 mc. of gold was instilled into the bladder for four to six hours to deliver a dose of about 4,000 to 5,000 r to the bladder epithelium. The treatment had no harmful side-effects locally or on the general condition of the patient. Three selected cases suitable for radioactive gold therapy are briefly reported; It is our impression that this method is an excellent type of irradiation for really superficial malignant lesions. The method was used for treatment of multiple papillomatosis of the bladder alone or in conjunction with surgery.