论文信息 - Dual-wavelength tissue ablation concept for laser prostatectomy with the Nd:YAG/KTP laser

Dual-wavelength tissue ablation concept for laser prostatectomy with the Nd:YAG/KTP laser

The Nd:YAG/KTP laser offers to the surgeon two wavelengths that can be used to coagulate and vaporize. Our objective was to investigate the combined effect of both wavelengths and to determine the irradiation parameters allowing the largest lesion volume. Chicken breast was irradiated ex vivo. 1064 nm and 532 nm Nd:YAG/KTP laser irradiations were performed sequentially at different combinations with variable fluence and compared to isofluent single wavelengths 40 W irradiation. Although the mean total lesion volume showed no difference between the different wavelengths combinations a significant enhancement of the maximum lesion depth was found under combined irradiation in the 20W/20W conditions. Dual wavelengths irradiation with the Nd:YAG/KTP laser thus induces a specific denaturation process which is more directional and results in an increased total lesion depth. This may represent a ne approach to increase the depth of coagulation necrosis and thus the total lesion volume, thereby improving long term results.

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