The association between aging-related monocyte transcriptional networks and comorbidity burden: the Multi-Ethnic Study of Atherosclerosis (MESA)

[1]  S. Yi,et al.  New Insights into the Role of Histone Changes in Aging , 2020, International journal of molecular sciences.

[2]  Kyung‐Jin Min,et al.  Mechanisms of Lifespan Regulation by Calorie Restriction and Intermittent Fasting in Model Organisms , 2020, Nutrients.

[3]  M. Ezzati,et al.  Multimorbidity-a defining challenge for health systems. , 2019, The Lancet. Public health.

[4]  C. Caruso,et al.  Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention , 2019, Front. Immunol..

[5]  R. Haas Mitochondrial Dysfunction in Aging and Diseases of Aging , 2019, Biology.

[6]  M. Benhamou,et al.  Understanding Fc Receptor Involvement in Inflammatory Diseases: From Mechanisms to New Therapeutic Tools , 2019, Front. Immunol..

[7]  J. Debnath,et al.  Autophagy and the cell biology of age-related disease , 2018, Nature Cell Biology.

[8]  L. Ferrucci,et al.  A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup , 2018, GeroScience.

[9]  J. Houseley,et al.  Gene expression hallmarks of cellular ageing , 2018, Biogerontology.

[10]  V. Labunskyy,et al.  Emerging Omics Approaches in Aging Research. , 2017, Antioxidants & redox signaling.

[11]  Jennifer G. Robinson,et al.  Clinical Trials Targeting Aging and Age-Related Multimorbidity , 2016, The journals of gerontology. Series A, Biological sciences and medical sciences.

[12]  Andres Metspalu,et al.  The transcriptional landscape of age in human peripheral blood , 2015, Nature Communications.

[13]  B. Diamond,et al.  Fundamental role of C1q in autoimmunity and inflammation , 2015, Immunologic Research.

[14]  J. Tower Programmed cell death in aging , 2015, Ageing Research Reviews.

[15]  Ina Hoeschele,et al.  Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease , 2015, Diabetes.

[16]  D. Jacobs,et al.  Transcriptomic profiles of aging in purified human immune cells , 2015, BMC Genomics.

[17]  Eric H. Baehrecke,et al.  Self-consumption: the interplay of autophagy and apoptosis , 2014, Nature Reviews Molecular Cell Biology.

[18]  B. Ames,et al.  Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males , 2013, Aging cell.

[19]  Erik D Herzog,et al.  Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. , 2013, Cell metabolism.

[20]  E. Mercken,et al.  Metformin improves healthspan and lifespan in mice , 2013, Nature Communications.

[21]  L. Partridge,et al.  The Hallmarks of Aging , 2013, Cell.

[22]  Cynthia M Boyd,et al.  Designing health care for the most common chronic condition--multimorbidity. , 2012, JAMA.

[23]  F. Tacke,et al.  Monocytes in health and disease - Minireview. , 2012, European journal of microbiology & immunology.

[24]  S. Wong,et al.  The three human monocyte subsets: implications for health and disease , 2012, Immunologic Research.

[25]  D. Rubinsztein,et al.  Autophagy and Aging , 2011, Cell.

[26]  R. de Cabo,et al.  Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. , 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

[27]  Xia Yang,et al.  Integrating pathway analysis and genetics of gene expression for genome-wide association studies. , 2010, American journal of human genetics.

[28]  P. Deloukas,et al.  Common Regulatory Variation Impacts Gene Expression in a Cell Type–Dependent Manner , 2009, Science.

[29]  G. Church,et al.  Meta-analysis of age-related gene expression profiles identifies common signatures of aging , 2009, Bioinform..

[30]  S. Rubin,et al.  Effects of birth cohort and age on body composition in a sample of community-based elderly. , 2007, The American journal of clinical nutrition.

[31]  John D. Storey,et al.  Statistical significance for genomewide studies , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[32]  R. Kronmal,et al.  Multi-Ethnic Study of Atherosclerosis: objectives and design. , 2002, American journal of epidemiology.

[33]  S. Ryter,et al.  Autophagy in human health and disease. , 2013, The New England journal of medicine.

[34]  Brad T. Sherman,et al.  DAVID: Database for Annotation, Visualization, and Integrated Discovery , 2003, Genome Biology.

[35]  Manolis Tsiknakis,et al.  Maturation of a central , 1996 .