Immunotoxins: a new approach to cancer therapy.

[1]  A. Fauci,et al.  Selective abrogation of antigen-specific human B cell responses by antigen-ricin conjugates , 1982, The Journal of experimental medicine.

[2]  D. Mason,et al.  Selective killing of malignant cells in a leukaemic rat bone marrow using an antibody–ricin conjugate , 1982, Nature.

[3]  J. Uhr,et al.  In vivo therapy of a murine B cell tumor (BCL1) using antibody-ricin A chain immunotoxins , 1982, The Journal of experimental medicine.

[4]  G. Janossy,et al.  USE OF ANTI-T-CELL MONOCLONAL ANTIBODY OKT3 TO PREVENT ACUTE GRAFT-VERSUS-HOST DISEASE IN ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR ACUTE LEUKAEMIA , 1982, The Lancet.

[5]  D. Neville,et al.  Bone marrow transplantation across major histocompatibility barriers. V. Protection of mice from lethal graft-vs.-host disease by pretreatment of donor cells with monoclonal anti-Thy-1.2 coupled to the toxin ricin , 1982, Journal of Experimental Medicine.

[6]  J. Uhr,et al.  Selective killing of leukaemia cells by antibody–toxin conjugates: implications for autologous bone marrow transplantation , 1982, Nature.

[7]  L. Houston.  Transport of ricin A chain after prior treatment of mouse leukemia cells with ricin B chain. , 1982, The Journal of biological chemistry.

[8]  Dominique,et al.  Immunotoxins: Hybrid Molecules Combining High Specificity and Potent Cytotoxicity , 1982, Immunological reviews.

[9]  P. Thorpe,et al.  The Preparation and Cytotoxic Properties of Antibody‐Toxin Conjugates , 1982, Immunological reviews.

[10]  V. Raso.  Antibody Mediated Delivery of Toxic Molecules to Antigen Bearing Target Cells , 1982, Immunological reviews.

[11]  D. Neville,et al.  Monoclonal Antibody‐Ricin or Ricin A Chain Hybrids: Kinetic Analysis of Cell Killing for Tumor Therapy , 1982, Immunological reviews.

[12]  J. Uhr,et al.  Neoplastic B Cells as Targets for Antibody‐Ricin A Chain Immunotoxins , 1982, Immunological reviews.

[13]  J. Ritz,et al.  Monoclonal antibody-ricin A chain conjugate selectively cytotoxic for cells bearing the common acute lymphoblastic leukemia antigen. , 1982, Cancer research.

[14]  J. Uhr,et al.  BCL1, a murine model of prolymphocytic leukemia. II. Morphology and ultrastructure. , 1981, The American journal of pathology.

[15]  P. Isakson,et al.  BCL1, a murine model of prolymphocytic leukemia. I. Effect of splenectomy on growth kinetics and organ distribution. , 1981, The American journal of pathology.

[16]  R. Nowinski,et al.  Cell-specific cytotoxicity expressed by a conjugate of ricin and murine monoclonal antibody directed against thy 1.1 antigen. , 1981, Cancer research.

[17]  A. Finkelstein,et al.  Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[18]  J. T. Forbes,et al.  Inhibition of mouse spleen cell function by diphtheria toxin fragment A coupled to anti-mouse Thy-1.2 and by ricin A chain coupled to anti-mouse IgM. , 1981, Archives of biochemistry and biophysics.

[19]  D. C. Edwards,et al.  Cytotoxicity acquired by conjugation of an anti-Thy1.1 monoclonal antibody and the ribosome-inactivating protein, gelonin. , 1981, European journal of biochemistry.

[20]  P. Casellas,et al.  Immunotoxins: hybrid molecules of monoclonal antibodies and a toxin subunit specifically kill tumour cells , 1981, Nature.

[21]  J. Kersey,et al.  BONE MARROW TRANSPLANTATION ACROSS MAJOR HISTOCOMPATIBILITY BARRIERS IN MICE EFFECT OF ELIMINATION OF T CELLS FROM DONOR GRAFTS BY TREATMENT WITH MONOCLONAL THY‐1.2 PLUS COMPLEMENT OR ANTIBODY ALONE , 1981, Transplantation.

[22]  D. C. Edwards,et al.  Abrogation of the non-specific toxicity of abrin conjugated to anti-lymphocyte globulin. , 1981, Clinical and experimental immunology.

[23]  V. Raso,et al.  Specific cytotoxicity of a human immunoglobulin-directed Fab'-ricin A chain conjugate. , 1980, Journal of immunology.

[24]  P. Casellas,et al.  High specific cytotoxicity of antibody-toxin hybrid molecules (immunotoxins) for target cells , 1980 .

[25]  D. Gilliland,et al.  A model system involving anti-concanavalin A for antibody targeting of diphtheria toxin fragment A1. , 1980, Cancer research.

[26]  E. Puré,et al.  The Activation of Murine B Cells: The Role of Surface Immunoglobulins , 1980, Immunological reviews.

[27]  D. Neville,et al.  Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[28]  P. Isakson,et al.  Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[29]  D. Gilliland,et al.  Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[30]  D. C. Edwards,et al.  Increased toxicity of diphtheria toxin for human lymphoblastoid cells following covalent linkage to anti-(human lymphocyte) globulin or its F(ab')2 fragment. , 1980, European journal of biochemistry.

[31]  S. Slavin,et al.  The role of the spleen in tumor growth kinetics of the murine B cell leukemia (BCL1). , 1980, Journal of immunology.

[32]  P. Isakson,et al.  BCL1, a Murine Model for Chronic Lymphocytic Leukemia: Use of the Surface Immunoglobulin Idiotype for the Detection and Treatment of Tumor , 1979, Immunological reviews.

[33]  Y. Masuho,et al.  Preparation of a hybrid of fragment Fab' of antibody and fragment A of diphtheria toxin and its cytotoxicity. , 1979, Biochemical and biophysical research communications.

[34]  L. Lanier,et al.  Antigen-induced murine B cell lymphomas. II. Exploitation of the surface idiotype as tumor specific antigen. , 1978, Journal of immunology.

[35]  J. Sprent,et al.  Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow , 1978, The Journal of experimental medicine.

[36]  H. Kunkel,et al.  Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[37]  D. C. Edwards,et al.  Toxicity of diphtheria toxin for lymphoblastoid cells is increased by conjugation to antilymphocytic globulin , 1978, Nature.

[38]  R. Warnke,et al.  The monoclonality of human B-cell lymphomas , 1977, The Journal of experimental medicine.

[39]  D. Hough,et al.  Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes , 1976, The Journal of experimental medicine.

[40]  R. Winchester,et al.  Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes. , 1975, Journal of immunology.

[41]  A. Pihl,et al.  Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis. , 1973, Biochemistry.

[42]  M. Tyan.  MODIFICATION OF SEVERE GRAFT‐VERSUS‐HOST DISEASE WITH ANTISERA TO THE &thetas; ANTIGEN OR TO WHOLE SERUM , 1973, Transplantation.

[43]  J. Kersey,et al.  Graft versus host reactions following transplantation of allogeneic hematopoietic cells. , 1971, Human pathology.

[44]  R. van Furth,et al.  THE ORIGIN AND KINETICS OF MONONUCLEAR PHAGOCYTES , 1968, The Journal of experimental medicine.

[45]  日本農芸化学会.  Agricultural and biological chemistry , 1961 .