Development of a desktop-sized thermal lens microscope

超高感度かつはん用性の高い,デスクトップサイズの熱レンズ顕微鏡(DT-TLM)を開発した.光学系の単純化と最適化によって,DT-TLMの操作性は従来の大型TLMに比較して大きく向上した.非蛍光性の色素分子(Sunset Yellow)水溶液を用いて性能評価したところ,色素分子濃度1×10-8~1×10-7 Mの範囲で良好な直線関係を示した.検量線の標準偏差(2σ)から定量下限値は1.10×10-8 M,S/N比(=2)から検出下限値は8.27×10-9 Mとそれぞれ見積もられた.これらの結果は大型TLMとほぼ同等の値であった.

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