A Novel Retinal Vessel Segmentation Method Using Connected Domain Merging and Improved Graph Cut

Retinal vessel segmentation is a key step in detecting diseases according to the retina, and the accuracy of blood vessel segmentation directly affects disease detection results. This paper proposes a novel algorithm to achieve fine segmentation of blood vessels, and the algorithm can also adapt to changes in the illumination of fundus images. Firstly, homomorphic filter is used to reduce the influence of non-uniform illumination. Secondly, the top-hat transform and Connected-Domain Merging are used to obtain a rough vessel segmentation and generate the candidate vessel. Finally, candidate vessel is expanded by morphological dilation to improve the contrast between target area and background area, and then improved graph cut algorithm is used to finely segment blood vessel. The proposed method is evaluated on STARE, DRIVE, and LES-AV, and the experiment result proves the effectiveness of the method.

[1]  Jin Liu,et al.  A variational model and graph cuts optimization for interactive foreground extraction , 2011, Signal Process..

[2]  Shyr-Shen Yu,et al.  Two improved k-means algorithms , 2017, Appl. Soft Comput..

[3]  David Zhang,et al.  Vessel segmentation and width estimation in retinal images using multiscale production of matched filter responses , 2012, Expert Syst. Appl..

[4]  David Zhang,et al.  A Modified Matched Filter With Double-Sided Thresholding for Screening Proliferative Diabetic Retinopathy , 2009, IEEE Transactions on Information Technology in Biomedicine.

[5]  Theocharis Theocharides,et al.  A high performance hardware architecture for portable, low-power retinal vessel segmentation , 2014, Integr..

[6]  A.D. Hoover,et al.  Locating blood vessels in retinal images by piecewise threshold probing of a matched filter response , 2000, IEEE Transactions on Medical Imaging.

[7]  Shankar M. Krishnan,et al.  Detection and measurement of retinal vessels in fundus images using amplitude modified second-order Gaussian filter , 2002, IEEE Transactions on Biomedical Engineering.

[8]  Simone Orcioni,et al.  Automatic decoding of input sinusoidal signal in a neuron model: High pass homomorphic filtering , 2018, Neurocomputing.

[9]  M. Goldbaum,et al.  Detection of blood vessels in retinal images using two-dimensional matched filters. , 1989, IEEE transactions on medical imaging.

[10]  J. Teng,et al.  Investigation on a novel bolted joint scheme for foam inserted top-hat stiffened composite plates , 2016 .

[11]  Elli Angelopoulou,et al.  Retinal vessel segmentation by improved matched filtering: evaluation on a new high-resolution fundus image database , 2013, IET Image Process..

[12]  Lei Zhang,et al.  Retinal vessel extraction by matched filter with first-order derivative of Gaussian , 2010, Comput. Biol. Medicine.