Somnomat: a novel actuated bed to investigate the effect of vestibular stimulation

Rocking movements are known to affect human sleep. Previous studies have demonstrated that the transition from wake to sleep can be facilitated by rocking movements, which might be related to relaxation. However, it is not yet known which movements would have the greatest effect. Thus, a 6-degree-of-freedom tendon-based robotic bed was developed, for systematic evaluation of vestibular stimuli. The applicability of the device was evaluated with 25 subjects. Six movement axes were tested and analyzed for differences in promoting relaxation. Relaxation was assessed by electroencephalogram, electrocardiogram, respiration and a questionnaire. The developed device fulfilled all needed requirements proving the applicability of this technology. Movements had no significant effects on the electroencephalogram and electrocardiogram. Respiration frequency was significantly lower for baseline measurements without movement (median 0.183–0.233 Hz) compared to movement conditions (median 0.283–0.300 Hz). Questionnaire ratings showed a trend (p = 0.057) toward higher relaxation for movements along the vertical axis (z-axis) (median 4.67; confidence interval 4.33–5.67) compared to the roll-axis (median 4.33; confidence interval 3.67–5.00). Movements along the vertical axis (z-axis), therefore, appear most promising in promoting relaxation, though no effects were found in electroencephalogram and electrocardiogram variables. This lack of effect might be attributed to the short exposure to the movements and the large inter-individual variability and individual preferences among subjects.

[1]  Kathrine Jáuregui-Renaud,et al.  Respiratory responses of normal and vestibular defective human subjects to rotation in the yaw and pitch planes , 2001, Neuroscience Letters.

[2]  Barbara Griefahn,et al.  Environmental noise and sleep. Review—Need for further research , 1991 .

[3]  Maurice M Ohayon,et al.  Epidemiology of insomnia: what we know and what we still need to learn. , 2002, Sleep medicine reviews.

[4]  Joachim von Zitzewitz r³ - reconfigurable rope robot as a versatile haptic interface for a cave automatic virtual environment , 2011 .

[5]  Roger B. Davis,et al.  Use of mind-body medical therapies , 2007, Journal of General Internal Medicine.

[6]  Anna Wirz-Justice,et al.  Circadian Clues to Sleep Onset Mechanisms , 2001, Neuropsychopharmacology.

[7]  A. Ertl,et al.  Influence of vestibular activation on respiration in humans. , 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

[8]  Robert Riener,et al.  A reconfigurable, tendon-based haptic interface for research into human-environment interactions , 2012, Robotica.

[9]  T. Borkovec,et al.  Critical procedural variables related to the physiological effects of progressive relaxation: a review. , 1979, Behaviour research and therapy.

[10]  B. Berglund,et al.  Guidelines for community noise , 1999 .

[11]  Atul Malhotra,et al.  The effect of vestibular stimulation in a four-hour sleep phase advance model of transient insomnia. , 2010, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[12]  J. Beary,et al.  The Relaxation Response †. , 1974, Psychiatry.

[13]  D. Dinges,et al.  Behavioral and physiological consequences of sleep restriction. , 2007, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[14]  A. Rechtschaffen,et al.  A manual of standardized terminology, technique and scoring system for sleep stages of human subjects , 1968 .

[15]  G. D. Jacobs,et al.  EEG Spectral Analysis of Relaxation Techniques , 2004, Applied psychophysiology and biofeedback.

[16]  J. Polich,et al.  Meditation states and traits: EEG, ERP, and neuroimaging studies. , 2013 .

[17]  Marko Munih,et al.  Psychophysiological responses to different levels of cognitive and physical workload in haptic interaction , 2010, Robotica.

[18]  M. Thorpy,et al.  Effects of Otolithic Vestibular Stimulation on Sleep. , 1990, Sleep.

[19]  C. Ray,et al.  Aging attenuates the vestibulorespiratory reflex in humans , 2003, The Journal of physiology.

[20]  Alex M. Andrew Nanomedicine, Volume 1: Basic Capabilities, by Robert A. Freitas Jr., Landes Bioscience, Austin, Texas, 1999, xxi + 509 pp., ISBN 1-57059-645-X Index (Hardback, $89.000) , 2000, Robotica.

[21]  Walter Magerl,et al.  The effect of deep and slow breathing on pain perception, autonomic activity, and mood processing--an experimental study. , 2012, Pain medicine.

[22]  Herbert Benson,et al.  The relaxation response: its subjective and objective historical precedents and physiology , 1983, Trends in Neurosciences.

[23]  Peter Wolf,et al.  Real‐time rowing simulator with multimodal feedback , 2008 .

[24]  Gin S Malhi,et al.  The psychological and neurophysiological concomitants of mindfulness forms of meditation , 2007, Acta Neuropsychiatrica.

[25]  Robert Riener,et al.  A versatile wire robot concept as a haptic interface for sport simulation , 2009, 2009 IEEE International Conference on Robotics and Automation.

[26]  C. L. Mandle,et al.  The efficacy of relaxation response interventions with adult patients: a review of the literature. , 1996, The Journal of cardiovascular nursing.

[27]  Carolina Cruz-Neira,et al.  Surround-Screen Projection-Based Virtual Reality: The Design and Implementation of the CAVE , 2023 .

[28]  E. Wolpert A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. , 1969 .

[29]  Anna Wirz-Justice,et al.  Physiology: Warm feet promote the rapid onset of sleep , 1999, Nature.

[30]  Mary A. Carskadon,et al.  Chapter 2 – Normal Human Sleep: An Overview , 2017 .

[31]  M. Mühlethaler,et al.  Rocking synchronizes brain waves during a short nap , 2011, Current Biology.

[32]  Arnaud Delorme,et al.  EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis , 2004, Journal of Neuroscience Methods.

[33]  A. Chesson,et al.  The American Academy of Sleep Medicine (AASM) Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications , 2007 .

[34]  Reshma Kaushik,et al.  Effects of mental relaxation and slow breathing in essential hypertension. , 2006, Complementary therapies in medicine.

[35]  Bea Tiemens,et al.  Music-assisted relaxation to improve sleep quality: meta-analysis. , 2009, Journal of advanced nursing.

[36]  Robert Riener,et al.  Robotic platform to investigate the effects of vestibular stimulation on sleep , 2011 .

[37]  Robert Riener,et al.  Forward kinematics of redundantly actuated, tendon-based robots , 2010, 2010 IEEE/RSJ International Conference on Intelligent Robots and Systems.

[38]  A. Alter,et al.  Device-guided breathing exercises reduce blood pressure: ambulatory and home measurements. , 2000, American journal of hypertension.

[39]  Luciano Bernardi,et al.  Slow Breathing Improves Arterial Baroreflex Sensitivity and Decreases Blood Pressure in Essential Hypertension , 2005, Hypertension.

[40]  Sue Wilson,et al.  Pharmacological Treatment of Nocturnal Sleep Disturbances , 2010 .

[41]  Alan D. Miller,et al.  Vestibular effects on upper airway musculature , 1996, Brain Research.