Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

[1]  R. Gibbs,et al.  Alu-primed polymerase chain reaction for regional assignment of 110 yeast artificial chromosome clones from the human X chromosome: identification of clones associated with a disease locus. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[2]  D. Schlessinger,et al.  Fragile X genotype characterized by an unstable region of DNA , 1991, Science.

[3]  A. Roche,et al.  Linear order of new and established DNA markers around the fragile site at Xq27.3. , 1991, Genomics.

[4]  D. Le Paslier,et al.  Isolation of sequences that span the fragile X and identification of a fragile X-related CpG island. , 1991, Science.

[5]  K. Davies,et al.  Physical mapping across the fragile X: Hypermethylation and clinical expression of the fragile X syndrome , 1991, Cell.

[6]  C. Petit,et al.  Abnormal pattern detected in fragile-X patients by pulsed-field gel electrophoresis , 1991, Nature.

[7]  P. Roepstorff,et al.  Cuttlefish sperm protamines. 2. Mass spectrometry of protamines and related peptides. , 1991, European journal of biochemistry.

[8]  E. Maestrini,et al.  Four chromosomal breakpoints and four new probes mark out a 10-cM region encompassing the fragile-X locus (FRAXA). , 1991, American journal of human genetics.

[9]  Brown Wt.  The fragile X: progress toward solving the puzzle. , 1990 .

[10]  D. Le Paslier,et al.  Construction and characterization of a yeast artificial chromosome library containing seven haploid human genome equivalents. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[11]  S. Warren,et al.  Isolation of the human chromosomal band Xq28 within somatic cell hybrids by fragile X site breakage. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[12]  B. Wieringa,et al.  New polymorphic DNA marker close to the fragile site FRAXA. , 1990, Genomics.

[13]  B. Roberts.  Nuclear location signal-mediated protein transport. , 1989, Biochimica et biophysica acta.

[14]  C. Tyler-Smith,et al.  Construction of yeast artificial chromosome libraries with large inserts using fractionation by pulsed-field gel electrophoresis. , 1989, Nucleic acids research.

[15]  Cosmid vector pCpG and plasmid vector pKNUN1, and their use for cloning DNA sequences adjacent to sites for rare cutting restriction endonucleases. , 1989, Nucleic acids research.

[16]  J. Wilson,et al.  Characterization and expression of a cDNA encoding the human androgen receptor. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[17]  J. Sutcliffe,et al.  Strategy for molecular cloning of the fragile X site DNA. , 1988, American journal of medical genetics.

[18]  C. Cantor,et al.  Pulsed-field gel electrophoresis and the technology of large DNA molecules. , 1988 .

[19]  The nucleotide sequence of a human protamine 1 cDNA. , 1987, Nucleic acids research.

[20]  S. Warren,et al.  The fragile X site in somatic cell hybrids: an approach for molecular cloning of fragile sites. , 1987, Science.

[21]  A. Bankier,et al.  Random cloning and sequencing by the M13/dideoxynucleotide chain termination method. , 1987, Methods in enzymology.

[22]  A. Bird,et al.  Use of restriction enzymes to detect potential gene sequences in mammalian DNA , 1987, Nature.

[23]  D. Ledbetter,et al.  Implications of fragile X expression in normal males for the nature of the mutation , 1986, Nature.

[24]  D. Ledbetter,et al.  Recombination and amplification of pyrimidine-rich sequences may be responsible for initiation and progression of the Xq27 fragile site: an hypothesis. , 1986, American journal of medical genetics.

[25]  G. Holmgren,et al.  Prevalence of the fragile-X syndrome in mentally retarded boys in a Swedish county. , 1986, American journal of medical genetics.

[26]  T. Webb,et al.  Population incidence and segregation ratios in the Martin-Bell syndrome. , 1986, American journal of medical genetics.

[27]  D. Ledbetter,et al.  A rodent-human hybrid containing Xq24-qter translocated to a hamster chromosome expresses the Xq27 folate-sensitive fragile site. , 1986, American journal of medical genetics.

[28]  G. Sutherland.  Fragile sites on human chromosomes , 1985 .

[29]  A. C. Chinault,et al.  Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[30]  N. Morton,et al.  The marker (X) syndrome: a cytogenetic and genetic analysis , 1984, Annals of human genetics.

[31]  A. Feinberg,et al.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. , 1983, Analytical biochemistry.

[32]  P. Thomas,et al.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[33]  E. Southern.  Detection of specific sequences among DNA fragments separated by gel electrophoresis. , 1975, Journal of molecular biology.

[34]  P. Leder,et al.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. , 1972, Proceedings of the National Academy of Sciences of the United States of America.