Using a Microwave Sensor as an Online Indicator of Neurological Impairment during Surgical Procedures

Lactate is known to be an indicator of neurological impairment during aortic aneurysm surgery. It is suggested that analysis of cerebrospinal fluid (CSF) removed during such surgery could provide useful information in this regard. Medical professionals find the prospect of online detection of such analytes exciting, as current practice is time consuming and leads to multiple invasive procedures. Advancing from the current laboratory based analysis techniques to online methods could provide the basis for improved treatment regimes, better quality of care, and enhanced resource efficiency within hospitals. Accordingly, this article considers the use of a low power microwave sensor to detect varying lactate concentrations. Microwave sensors provide a rapid non-invasive method of material analysis, which is robust, cost-effective, and has huge potential for a wide range of biomedical applications.

[1]  J. H. Goh,et al.  Lactate Detection using Microwave Spectroscopy for In-Situ Medical Applications , 2011 .

[2]  M. Higgins.  Data for Biochemical Research, 3rd Edition , 1987 .

[3]  Alex Mason,et al.  Monitoring of Nitrates and Phosphates in Wastewater: Current Technologies and Further Challenges , 2012 .

[4]  A. Al-Shamma'a,et al.  Lipid droplet detection by the cavity perturbation method , 2011 .

[5]  A. Mason,et al.  Dielectric characteristics of lipid droplets suspended in YEPD media , 2011, 2011 Fifth International Conference on Sensing Technology.

[6]  Alex Mason,et al.  Use of Sensors in Wastewater Quality Monitoring—A Review of Available Technologies , 2011 .

[7]  S. Frank,et al.  Changes in Cerebrospinal Fluid Pressure and Lactate Concentrations during Thoracoabdominal Aortic Aneurysm Surgery , 1997, Anesthesiology.

[8]  Hiroshi Tamura,et al.  Low Temperature Properties of Microwave Dielectrics , 1989 .

[9]  G. Ronquist,et al.  Central nervous system damage during cardiac surgery assessed by 3 different biochemical markers in cerebrospinal fluid. , 1992, Scandinavian journal of thoracic and cardiovascular surgery.

[10]  J. Sheen.  Amendment of Cavity Perturbation Technique for Loss Tangent Measurement at Microwave Frequencies , 2006, 2006 7th International Symposium on Antennas, Propagation & EM Theory.

[11]  Amendment of cavity perturbation technique for loss tangent measurement at microwave frequencies , 2007 .

[12]  Jyh Sheen,et al.  Measurements of microwave dielectric properties by an amended cavity perturbation technique , 2009 .

[13]  D. Kajfez.  Temperature characterization of dielectric-resonator materials , 2001 .

[14]  H. Borst,et al.  The mechanism of spinal cord injury after simple and double aortic cross-clamping. , 1986, The Journal of thoracic and cardiovascular surgery.

[15]  L. Hansson,et al.  Biochemical markers of cerebrospinal ischemia after repair of aneurysms of the descending and thoracoabdominal aorta. , 2003, Journal of cardiothoracic and vascular anesthesia.

[16]  S. R. Wylie,et al.  Lactate detection using a microwave cavity sensor for biomedical applications , 2011, 2011 Fifth International Conference on Sensing Technology.