The effects of mindfulness-based stress reduction therapy on mental health of adults with a chronic medical disease: a meta-analysis.

OBJECTIVES The objective of this study was to examine the effectiveness of mindfulness-based stress reduction (MBSR) on depression, anxiety and psychological distress across populations with different chronic somatic diseases. METHODS A systematic review and meta-analysis were performed to examine the effects of MBSR on depression, anxiety, and psychological distress. The influence of quality of studies on the effects of MBSR was analyzed. RESULTS Eight published, randomized controlled outcome studies were included. An overall effect size on depression of 0.26 was found, indicating a small effect of MBSR on depression. The effect size for anxiety was 0.47. However, quality of the studies was found to moderate this effect size. When the studies of lower quality were excluded, an effect size of 0.24 on anxiety was found. A small effect size (0.32) was also found for psychological distress. CONCLUSIONS It can be concluded that MBSR has small effects on depression, anxiety and psychological distress in people with chronic somatic diseases. Integrating MBSR in behavioral therapy may enhance the efficacy of mindfulness based interventions.

[1]  Kristalyn Salters-Pedneault,et al.  Efficacy of an acceptance-based behavior therapy for generalized anxiety disorder: evaluation in a randomized controlled trial. , 2008, Journal of consulting and clinical psychology.

[2]  Steven C Hayes,et al.  ScholarWorks @ Georgia State University , 2018 .

[3]  S. Patten,et al.  Long-term medical conditions and major depression in a Canadian population study at waves 1 and 2. , 2001, Journal of affective disorders.

[4]  P. Poli,et al.  Assessment of depression among cancer patients: the role of pain, cancer type and treatment , 2001, Psycho-oncology.

[5]  W. Hauck,et al.  A randomized, controlled trial of mindfulness‐based art therapy (MBAT) for women with cancer , 2006, Psycho-oncology.

[6]  C. Surawy,et al.  The Effect of Mindfulness Training on Mood and Measures of Fatigue, Activity, and Quality of Life in Patients with Chronic Fatigue Syndrome on a Hospital Waiting List: A Series of Exploratory Studies , 2005, Behavioural and Cognitive Psychotherapy.

[7]  G. Andersson,et al.  The effects of psychotherapy for adult depression are overestimated: a meta-analysis of study quality and effect size , 2009, Psychological Medicine.

[8]  M. Lipsey,et al.  The efficacy of psychological, educational, and behavioral treatment. Confirmation from meta-analysis. , 1993, American Psychologist.

[9]  D. Weiner,et al.  Mindfulness meditation for the treatment of chronic low back pain in older adults: A randomized controlled pilot study , 2008, PAIN.

[10]  David R. Williams,et al.  Mental disorders among persons with heart disease - results from World Mental Health surveys. , 2008, General hospital psychiatry.

[11]  J. Weisz,et al.  Effects of psychotherapy for depression in children and adolescents: a meta-analysis. , 2006, Psychological bulletin.

[12]  J. Kabat-Zinn,et al.  Full catastrophe living : using the wisdom of your body and mind to face stress, pain, and illness , 1990 .

[13]  Z. Segal,et al.  Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. , 2000, Journal of consulting and clinical psychology.

[14]  P. Grossman,et al.  Mindfulness-based stress reduction and health benefits: A meta-analysis , 2004, Journal of Psychosomatic Research.

[15]  Enrique Sanchez-Delgado,et al.  Lifetime risk of developing coronary heart disease , 1999, The Lancet.

[16]  P. Coventry,et al.  Improving outcomes for COPD patients with mild-to-moderate anxiety and depression: a systematic review of cognitive behavioural therapy. , 2008, British journal of health psychology.

[17]  R. Baer.  Mindfulness Training as a Clinical Intervention: A Conceptual and Empirical Review , 2003 .

[18]  D. Altman,et al.  Measuring inconsistency in meta-analyses , 2003, BMJ : British Medical Journal.

[19]  P. Salmon,et al.  Mindfulness meditation alleviates depressive symptoms in women with fibromyalgia: results of a randomized clinical trial. , 2007, Arthritis and rheumatism.

[20]  Richard G. Moore,et al.  Metacognitive awareness and prevention of relapse in depression: empirical evidence. , 2002, Journal of consulting and clinical psychology.

[21]  L. Hedges,et al.  Statistical Methods for Meta-Analysis , 1987 .

[22]  P. Grossman,et al.  Mindfulness Training as an Intervention for Fibromyalgia: Evidence of Postintervention and 3-Year Follow-Up Benefits in Well-Being , 2007, Psychotherapy and Psychosomatics.

[23]  J. Kabat-Zinn,et al.  An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results. , 1982, General hospital psychiatry.

[24]  F. Blyth,et al.  Chronic pain in Australia: a prevalence study , 2001, Pain.

[25]  D. Stewart,et al.  Psychiatric-Medical Comorbidity The Psychiatric-Medical Comorbidity section will focus on the prevalence and impact of psychiatric disorders in patients with chronic medical illness as well as the prevalence and impact of medical disorders in patients with chronic psychiatric illness. , 2009 .

[26]  J. Teasdale,et al.  Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects. , 2004, Journal of consulting and clinical psychology.

[27]  M. Hochberg,et al.  The efficacy of mindfulness meditation plus Qigong movement therapy in the treatment of fibromyalgia: a randomized controlled trial. , 2003, The Journal of rheumatology.

[28]  P. Lehrer,et al.  Psychosocial Treatments for Multiple Unexplained Physical Symptoms: A Review of the Literature , 2002, Psychosomatic medicine.

[29]  M. Artés,et al.  Prevalence of pain in the Spanish population telephone survey in 5000 homes , 2002, European journal of pain.

[30]  L. Carlson,et al.  A Randomized, Wait-List Controlled Clinical Trial: The Effect of a Mindfulness Meditation-Based Stress Reduction Program on Mood and Symptoms of Stress in Cancer Outpatients , 2000, Psychosomatic medicine.

[31]  M. Hochberg,et al.  Effect of Mindfulness-Based Stress Reduction in rheumatoid arthritis patients. , 2007, Arthritis and rheumatism.

[32]  S. Hollon,et al.  Defining empirically supported therapies. , 1998, Journal of consulting and clinical psychology.

[33]  Yvonne M. Caldera,et al.  Mindfulness Meditation, Anxiety Reduction, and Heart Disease: A Pilot Study , 2003, Family & community health.

[34]  R. Jacobs,et al.  Cognitive-behavioral therapy for adolescent depression: a meta-analytic investigation of changes in effect-size estimates. , 2007, Journal of the American Academy of Child and Adolescent Psychiatry.

[35]  Z. Segal,et al.  How does cognitive therapy prevent depressive relapse and why should attentional control (mindfulness) training help? , 1995, Behaviour research and therapy.