Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors.
暂无分享,去创建一个
A. Cavalli | L. Piazzi | F. Belluti | A. Bisi | S. Gobbi | M. Bartolini | A. Rampa | P. Valenti | Lorna Piazzi
[1] L. Horner,et al. Die Synthese brückenanaloger Thyroninverbindungen , 1952 .
[2] R. Bartus,et al. The cholinergic hypothesis of geriatric memory dysfunction. , 1982, Science.
[3] H. Brodaty,et al. THA and Alzheimer's disease. , 1987, The Australian and New Zealand journal of psychiatry.
[4] Galanthamine treatment in Alzheimer's disease. , 1991, Journal of neural transmission. Supplementum.
[5] H. Sugimoto,et al. Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride and related compounds. , 1995, Journal of medicinal chemistry.
[6] N. Inestrosa,et al. Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-β-peptides , 1995, Neuroscience Letters.
[7] Claudia Linker,et al. Acetylcholinesterase Accelerates Assembly of Amyloid-β-Peptides into Alzheimer's Fibrils: Possible Role of the Peripheral Site of the Enzyme , 1996, Neuron.
[8] P Willett,et al. Development and validation of a genetic algorithm for flexible docking. , 1997, Journal of molecular biology.
[9] L. Kelley,et al. An automated approach for defining core atoms and domains in an ensemble of NMR-derived protein structures. , 1997, Protein engineering.
[10] Joel L. Sussman,et al. Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo californica , 1998, Journal of Physiology-Paris.
[11] C. Spencer,et al. Rivastigmine. A review of its use in Alzheimer's disease. , 1998, Drugs & aging.
[12] N. Ariel,et al. Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II. , 2000, Acta crystallographica. Section D, Biological crystallography.
[13] D. Learmonth. RAPID MICROWAVE-PROMOTED SYNTHESIS OF FUNCTIONALISED BENZOPHENONES , 2002 .
[14] V. Andrisano,et al. beta-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies. , 2003, Biochemical pharmacology.
[15] A. Cavalli,et al. 3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy. , 2003, Journal of medicinal chemistry.
[16] Andrea Cavalli,et al. A Comparative Study on the Application of Hierarchical-Agglomerative Clustering Approaches to Organize Outputs of Reiterated Docking Runs , 2006, J. Chem. Inf. Model..
[17] V. Andrisano,et al. Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones. , 2007, Bioorganic & medicinal chemistry.