Silica nanoparticles doped with a europium(III) complex and coated with an ion imprinted polymer for rapid determination of copper(II)

AbstractWe have prepared highly monodisperse silica spheres doped with an Eu(III) complex and coated them with a nanoshell of a copper-imprinted polymer. The silica cores have a diameter of 200 nm, and the nanoshells have a thickness of 10–30 nm. The nanoparticles were characterized by means of scanning electron microscopy and transmission electron microscopy. The material is shown to be a viable fluorescent probe for Cu(II) ions. The surface molecular imprint renders the nanoprobe sensitive and selective. It was successfully applied to the detection of Cu(II) and gave a linear fluorescent response in the 10–100 μM concentration range. Compared to other methods, this one features high selectivity, sensitivity, low cost and ease of operation. We assume that this assay is applicable to routine trace determination of Cu(II) in water or biological environments. By adopting the appropriate functional monomers, cross-linking agents and template ions, the method can potentially be used to fabricate a highly selective imprinted probe for other heavy and transition metal ions. Graphical AbstractThe europium complex fluorescent probe detected the content of divalent copper by surface ion imprinting. The imprinted shell of the probe bound Cu(II) rapidly and selectively. Due to Cu(II) quenching of the fluorescent core, the fluorescence intensity decreases.

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