Uremic Cardiomyopathy—An Endogenous Digitalis Intoxication?: Central Role for the Cardiotonic Steroid Marinobufagenin in the Pathogenesis of Experimental Uremic Cardiomyopathy. Hypertension 47: 488–495, 2006

Since the days of Richard Bright ([1][1]), it has been common knowledge that the heart is a target organ in uremia, and by the beginning of the 20th century it had been recognized that heart failure and cardiac death were frequent in renal patients ([2][2]). Despite the common occurrence of failing

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