Analysis of traumatic brain injury due to primary head contact during vehicle-to-pedestrian impact

We developed a 50th-percentile American male pedestrian model including a detailed brain, and the mechanical responses and kinematic biofidelity predicted by this model were validated against the available cadaveric test data. Vehicle-to-pedestrian impact simulations were then performed to investigate a potential mechanism for traumatic brain injury resulting from a lateral blunt impact to the head. Due to inertia of the brain mass, it was found that the average traction force produced in the cervical spinal cord exceeded 50 N in the impact involving a sport utility vehicle and 25 N in the impact involving a sedan, when the striking vehicle was travelling at 40 km/h. This inertial loading may play a key role in a brainstem, or upper-cervical-cord, lesion occurring before head strike. Results of this study suggest that close attention should be paid to pedestrian kinematics during free flight even before the head makes primary contact with the striking vehicle.

[1]  Hirotoshi Ishikawa,et al.  SUMMARY OF IHRA PEDESTRIAN SAFETY WG ACTIVITIES (2005) - PROPOSED TEST METHODS TO EVALUATE PEDESTRIAN PROTECTION AFFORDED BY PASSENGER CARS , 2001 .

[2]  Dietmar Otte,et al.  Pedestrian Impact Priorities Using Real-World Crash Data and Harm , 2004 .

[3]  Christopher J. Brown,et al.  Impact mechanics and axonal injury in a sheep model. , 2003, Journal of neurotrauma.

[4]  Jason R. Kerrigan,et al.  Kinematic comparison of the Polar-II and PMHS in pedestrian impact tests with a sport-utility vehicle , 2005 .

[5]  Susan S. Margulies,et al.  IN VIVO MOTION OF THE HUMAN CERVICAL SPINAL CORD IN EXTENSION AND FLEXION , 1992 .

[6]  K O'Riordain,et al.  Reconstruction of real world head injury accidents resulting from falls using multibody dynamics. , 2003, Clinical biomechanics.

[7]  Takeo Matsumoto,et al.  Measurement of Nerve Fiber Strain in Brain Tissue Subjected to Uniaxial Stretch (Comparison Between Local Strain of Nerve Fiber and Global Strain of Brain Tissue) , 2006 .

[8]  Michael D. Gilchrist,et al.  The creation of three-dimensional finite element models for simulating head impact biomechanics , 2003 .

[9]  Takeo Matsumoto,et al.  Mechanical Characterization of Brain Tissue in High-Rate Compression , 2007 .

[10]  J. Hasegawa,et al.  A STUDY OF WHIPLASH INJURY OCCURRENCE MECHANISMS USING HUMAN FINITE ELEMENT MODEL , 2003 .

[11]  B S Roudsari,et al.  Pedestrian crashes: higher injury severity and mortality rate for light truck vehicles compared with passenger vehicles , 2004, Injury Prevention.

[12]  Claude Tarriere,et al.  Development of a F.E.M. of the human head according to a specific test protocol , 1992 .

[13]  Jason R. Kerrigan,et al.  Design of a Full-Scale Impact System for Analysis of Vehicle Pedestrian Collisions , 2005 .

[14]  Svein Kleiven,et al.  Correlation of an FE Model of the Human Head with Local Brain Motion--Consequences for Injury Prediction. , 2002, Stapp car crash journal.

[15]  Jeffrey Richard Crandall,et al.  The Causes of Head Injury in Vehicle-Pedestrian Impacts: Comparing the Relative Danger of Vehicle and Road Surface , 2006 .

[16]  Denis P. Wood,et al.  Effects of pre-impact pedestrian position and motion on kinematics and injuries from vehicle and ground contact , 2006 .

[17]  Reinhard Grebe,et al.  Tensile strength of cranial pia mater: preliminary results. , 2004, Journal of neurosurgery.

[18]  Yutaka Okamoto,et al.  A Study of Pedestrian Head Injury Evaluation Method , 2006 .

[19]  Rémy Willinger,et al.  Human Head FE Modelling: Improvement of Skull Geometry and Brain Constitutive Laws , 2004 .

[20]  M D Gilchrist,et al.  The use of accident reconstruction for the analysis of traumatic brain injury due to head impacts arising from falls , 2006, Computer methods in biomechanics and biomedical engineering.

[21]  Jason R. Kerrigan,et al.  Thoracic deformation response of pedestrians resulting from vehicle impact , 2006 .

[22]  Charles DiMaggio,et al.  The association of light trucks and vans with paediatric pedestrian deaths , 2006, International journal of injury control and safety promotion.

[23]  Svein Kleiven,et al.  Evaluation of head injury criteria using a finite element model validated against experiments on localized brain motion, intracerebral acceleration, and intracranial pressure , 2006 .

[24]  D F Meaney,et al.  Immediate coma following inertial brain injury dependent on axonal damage in the brainstem. , 2000, Journal of neurosurgery.

[25]  Rikard Fredriksson,et al.  Influence of Pop-up Hood Systems on Brain Injuries for Vulnerable Road Users , 2006 .

[26]  N. Yoganandan,et al.  Force and Acceleration Corridors from Lateral Head Impact , 2004, Traffic injury prevention.

[27]  King H. Yang,et al.  Investigation of Head Injury Mechanisms Using Neutral Density Technology and High-Speed Biplanar X-ray. , 2001, Stapp car crash journal.

[28]  W Goldsmith,et al.  Biomechanics and neuropathology of adult and paediatric head injury , 2002, British journal of neurosurgery.

[29]  Jingzhen Yang.  Review of Injury Biomechanics in Car-Pedestrian Collisions , 2005 .

[30]  Robert Anderson,et al.  Determining Accurate Contact Definitions in Multi-Body Simulations for DOE-Type Reconstruction of Head Impacts in Pedestrian Accidents , 2005 .

[31]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.

[32]  J. Crandall,et al.  Designing road vehicles for pedestrian protection , 2002, BMJ : British Medical Journal.

[33]  T. Yasuki,et al.  The influence of the Traction Force due to Inertia of the Brain Mass on Traumatic Brain Injury during SUV-to-Pedestrian Impact , 2006 .

[34]  D. Meaney,et al.  Tissue-level thresholds for axonal damage in an experimental model of central nervous system white matter injury. , 2000, Journal of biomechanical engineering.

[35]  Rolf H. Eppinger,et al.  A Three-Dimensional Finite Element Analysis of the Human Brain Under Combined Rotational and Translational Accelerations , 1994 .

[36]  T. Ohshima,et al.  Fatal injuries of the brain stem and/or upper cervical spinal cord in traffic accidents: nine autopsy cases. , 1995, Science & justice : journal of the Forensic Science Society.

[37]  Dietmar Otte,et al.  Analysis and load assessment of secondary impact to adult pedestrians after car collisions on roads , 2001 .

[38]  I. Mizusawa,et al.  The mechanism underlying the occurrence of traumatic brainstem lesions in victims of traffic accidents. , 2002, Legal medicine.

[39]  T. J. Horgan,et al.  Influence of FE model variability in predicting brain motion and intracranial pressure changes in head impact simulations , 2004 .

[40]  Giulio Ponte,et al.  Pedestrian subsystem head impact results reflect the severity of pedestrian head injuries , 2003 .

[41]  Check Y. Kam,et al.  Kinematic Corridors for PMHS Tested in Full-Scale Pedestrian Impact Tests , 2005 .

[42]  L Zhang,et al.  Recent advances in brain injury research: a new human head model development and validation. , 2001, Stapp car crash journal.

[43]  Hampton C Gabler,et al.  The fatality and injury risk of light truck impacts with pedestrians in the United States. , 2004, Accident; analysis and prevention.