Induced chorioretinal venous anastomosis in experimental retinal branch vein occlusion.

Iatrogenic retinal vein to choroidal vein anastomoses were created using laser photocoagulation in six of seven dog eyes in which a partial branch retinal vein occlusion had previously been created photochemically. A similar attempt to create an anastomosis was made in six control eyes in which no branch vein occlusion was present. In the eyes in which a branch retinal vein had been created, a venous chorioretinal anastomosis appeared to be present by 3 to 6 weeks. In three control eyes similar venous anastomosis was created; however this took 6 to 8 weeks to develop and was of much smaller calibre than the one that developed in the presence of a partial branch retinal vein occlusion. No adverse complications were noted in the period of the study (3 months). This study demonstrates that chorioretinal venous anastomoses can be created and may be of use in the treatment of partial retinal vein occlusions that show signs of progression.

[1]  T. Ashford,et al.  The role of the endothelium in the initial phases of thrombosis. An electron microscopic study. , 1967, The American journal of pathology.

[2]  S. Vannas,et al.  Experience of treating retinal venous occlusion with anticoagulant and antisclerosis therapy. , 1957, A.M.A. archives of ophthalmology.

[3]  J. Duker,et al.  Anterior location of the crossing artery in branch retinal vein obstruction. , 1989, Archives of ophthalmology.

[4]  M. Wiederholt,et al.  A randomised prospective study of treatment of non-ischaemic central retinal vein occlusion by isovolaemic haemodilution. , 1989, The British journal of ophthalmology.

[5]  M. Goldberg Chorioretinal vascular anastomoses after perforating trauma to the eye. , 1978, American journal of ophthalmology.

[6]  S. Tseng,et al.  Photothrombosis of corneal neovascularization by intravenous rose bengal and argon laser irradiation. , 1988, Archives of ophthalmology.

[7]  G A Peyman,et al.  Tissue plasminogen activator in the treatment of experimental retinal vein occlusion. , 1989, Retina.

[8]  M. Goldberg Choroidoretinal vascular anastomoses after blunt trauma to the eye. , 1976, American journal of ophthalmology.

[9]  M. Goldberg,et al.  Chorioretinal vascular anastomoses resulting from photocoagulation in cynomolgus monkeys. , 1980, Ophthalmic surgery.

[10]  F. Gutman,et al.  Partial occlusion of the central retinal vein. , 1983, American journal of ophthalmology.

[11]  B. Doft Choroidoretinal vascular anastomosis. , 1983, Archives of ophthalmology.

[12]  L. Hansen,et al.  The natural course of central retinal vein occlusion. , 1991, American journal of ophthalmology.

[13]  P. Owens,et al.  Prospective observation of vascular anastomoses between the retina and choroid in recurrent toxoplasmosis. , 1979, American journal of ophthalmology.

[14]  D. Archer,et al.  Morphologic fluorescein angiographic, and light microscopic features of experimental choroidal neovascularization. , 1981, American journal of ophthalmology.

[15]  S. Ryan,et al.  The development of an experimental model of subretinal neovascularization in disciform macular degeneration. , 1979, Transactions of the American Ophthalmological Society.

[16]  W R Green,et al.  Histopathologic study of nine branch retinal vein occlusions. , 1982, Archives of ophthalmology.

[17]  A. Bill The uveal venous pressure. , 1963, Archives of ophthalmology.

[18]  G. N. Wise,et al.  Retinochoroidal vascular anastomosis in uveitis. , 1971, American journal of ophthalmology.

[19]  E. Kohner,et al.  Panretinal photocoagulation in central retinal vein occlusion: A randomised controlled clinical study. , 1977, The British journal of ophthalmology.

[20]  R. Hessberg X-Ray Treatment of Thrombosis of the Retinal Vein and of Several Types of Iridocyclitis , 1944 .

[21]  R F Woolson,et al.  Ocular neovascularization with retinal vascular occlusion-III. Incidence of ocular neovascularization with retinal vein occlusion. , 1983, Ophthalmology.

[22]  W. Smith,et al.  Retinal vein occlusion. A comparative study of factors affecting the prognosis, including a therapeutic trial of Atromid S in this condition. , 1968, The British journal of ophthalmology.

[23]  W. Green,et al.  Senile Disciform Degeneration of the Macula: Retinal Arterialization of the Fibrous Plaque Demonstrated Clinically and Histopathologically , 1971, Archives of ophthalmology.

[24]  G. Hutchins,et al.  CENTRAL RETINAL VEIN OCCLUSION: A Prospective Histopathologic Study of 29 Eyes in 28 Cases , 2005, Retina.

[25]  G. Brown,et al.  Progression of nonischemic central retinal vein obstruction to the ischemic variant. , 1986, Ophthalmology.

[26]  B. Klien Occlusion of the central retinal vein; clinical importance of certain histopathologic observations. , 1953, American journal of ophthalmology.

[27]  H. Schatz Occlusion of the central retinal vein. , 1981, American journal of ophthalmology.

[28]  C. Bulpitt,et al.  Streptokinase in central retinal vein occlusion: a controlled clinical trial. , 1976, British medical journal.

[29]  W R Green,et al.  Senile macular degeneration: a histopathologic study. , 1977, Transactions of the American Ophthalmological Society.