Review of the Molecularly Imprinted Hydrogel In Chemical Analysis

The Molecularly Imprinted Hydrogel (MIH) is an insoluble polymer that the cavity has identical chemistry shape to the molecule target. This hydrogel is one of the Molecularly Imprinted Polymer (MIP) type commonly used in water solution. MIH is recently developed for chemical analysis needs. The MIH can give best analysis result. The analysis process should be aimed to get high accuracy and reproducibility in order to show the reliable result. It can be achieved by ensuring the supported instrument had similar character to the target molecule. The character is made by using the target molecule as an imprint in the polymer synthesis. After the extraction target molecule step, it will leave the identical cavity used to trap target molecule in the sample. The advantage of using MIH is the good result of external stimuli, such as pH, temperature, ionic strength, or electric field. Moreover, MIH can be used in various field. In pharmacy, MIH is used as carriers of drugs, proteins and glucose analysis which also show the stimuli-responsive behavior for its recognitions. Additionally, MIH is also used as separation media in particular direction such as food samples.