Analysis of drugs and related compounds by capillary column GLC

This article describes the development of the application of capillary column GLC methods to steroids, prostaglandins and especially drugs and their metabolites in samples of biological origin. The wide variety – in terms of structures and pharmacological properties – of drugs now analyzed by capillary column GLC is made evident. Reasons for use of capillary rather than packed columns are given. The frequent use of and need for derivatization procedures prior to chromatography is emphasized. A bibliography of 83 references is included in the manuscript.

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