Long-term Use of Intermittent Positive-Pressure Breathing (IPPB) in Chronic Obstructive Pulmonary Disease1, 2

The long-term use of intermittent positive-pressure breathing (IPPB) to deliver bronchodilator was compared to delivery by air compressor in 88 patients with chronic obstructive pulmonary disease who were in the home care program. There was no difference between the two groups in terms of number of hospital admissions, days spent in hospital, or mortality. The deterioration in ventilatory function was the same in both groups, although the patients receiving IPPB appeared to have developed greater hyperinflation. The data suggest that there is little evidence to support the long-term use of IPPB in the therapy of most patients with chronic obstructive pulmonary disease.

[1]  R. Cherniack,et al.  Normal standards for ventilatory function using an automated wedge spirometer. , 1972, The American review of respiratory disease.

[2]  B. J. Sobol,et al.  A study of the long-term effect of therapy in chronic obstructive pulmonary disease. , 1969, The American journal of medicine.

[3]  H. Rasmussen,et al.  IPPB Therapy in Chronic Obstructive Pulmonary Disease: An Evaluation of Long-Term Home Treatment , 1968 .

[4]  A. Renzetti,et al.  The Veterans Administration cooperative study of pulmonary function. 3. Mortality in relation to respiratory function in chronic obstructive pulmonary disease. , 1966, Aspen Emphysema Conference.

[5]  P. Lewis,et al.  Effects of intermittent positive pressure breathing on emphysematous patients. , 1966, The American journal of medicine.

[6]  W. Briscoe,et al.  The effect of intermittent positive pressure breathing and voluntary hyperventilation upon the distribution of ventilation and pulmonary blood flow to the lung in chronic obstructive lung disease. , 1966, The Journal of clinical investigation.

[7]  R. Cherniack,et al.  THE EFFECT OF NEBULIZED BRONCHODILATOR DELIVERED WITH AND WITHOUT IPPB ON VENTILATORY FUNCTION IN CHRONIC OBSTRUCTIVE EMPHYSEMA. , 2015, The American review of respiratory disease.

[8]  M. H. Williams,et al.  The effect of intermittent positive pressure breathing (IPPB) in acute ventilatory failure. , 1965, The American review of respiratory disease.

[9]  S. Ayres,et al.  THE EFFECTS OF INTERMITTENT POSITIVE PRESSURE BREATHING ON INTRATHORACIC PRESSURE, PULMONARY MECHANICS, AND THE WORK OF BREATHING1, 2, 3 , 2015 .

[10]  Bates Dv,et al.  A report on the first two stages of the co-ordinated study of chronic bronchitis in the Department of Veterans Affairs, Canada. , 1962 .

[11]  R. Cathcart,et al.  The use of intermittent positive pressure breathing in the prevention of the carbon dioxide narcosis associated with oxygen therapy. , 2015 .

[12]  H. Froeb.  On the relief of bronchospasm and the induction of alveolar hyperventilation: a comparative study of nebulized bronchodilators by deep breathing and intermittent positive pressure. , 1960, Diseases of the chest.

[13]  E. Gaensler,et al.  The effects of intermittent positive pressure breathing in simulated pulmonary obstruction. , 1960, The American review of respiratory disease.

[14]  M. I. Ferrer,et al.  Some effects of mechanical respirators upon respiratory gas exchange and ventilation in chronic pulmonary emphysema. , 1959, The American review of respiratory disease.

[15]  W. S. Fowler,et al.  The treatment of pulmonary emphysema and of diffuse pulmonary fibrosis with nebulized bronchodilators and intermittent positive pressure breathing. , 1955, Diseases of the chest.

[16]  W. F. Miller,et al.  Intermittent positive pressure breathing in patients with chronic bronchopulmonary disease; a comparative evaluation of the effects of intermittent positive pressure breathing alone, oxygen-nebulized bronchodilator alone, and the two procedures together. , 1955, American review of tuberculosis.

[17]  A. Barach.  The application of pressure, including exsufflation, in pulmonary emphysema. , 1955, American journal of surgery.

[18]  M. J. Dulfano,et al.  Intermittent positive pressure breathing; its use in the inspiratory phase of respiration. , 1954, The New England journal of medicine.

[19]  W. S. Fowler,et al.  Treatment of pulmonary emphysema with aerosolized bronchodilator drugs and intermittent positive-pressure breathing. , 1953, Proceedings of the staff meetings. Mayo Clinic.

[20]  H. L. Motley,et al.  Use of intermittent positive pressure breathing combined with nebulization in pulmonary disease. , 1948, The American journal of medicine.