Differential Determination of GOT Isoenzymes in Sera and Organs of Experimental Animals by the Immunochemical Method

It was revealed that the immunochemical isolation method for GOT isoenzymes, using anti pig c-GOT antibody, could be applicable for dogs, cats, rats, chickens and mice in addition to pigs and human. Mitochondrial-GOT/total-GOT (m-GOT/t-GOT) ratios were not necessarily close to one in various organs of each animal and furthermore the distributive differences among the corresponding organs of those species were also evidently recognized by this method.