Screening and Treating Hospitalized Trauma Survivors for PTSD and Depression.

Traumatic injury affects over 2.6 million U.S. adults annually and elevates risk for a number of negative health consequences. This includes substantial psychological harm, the most prominent being posttraumatic stress disorder (PTSD), with approximately 21% of traumatic injury survivors developing the disorder within the first year after injury. PTSD is associated with deficits in physical recovery, social functioning, and quality of life. Depression is diagnosed in approximately 6% in the year after injury and is also a predictor of poor quality of life. The American College of Surgeons Committee on Trauma suggests screening for and treatment of PTSD and depression, reflecting a growing awareness of the critical need to address patients' mental health needs after trauma. While some trauma centers have implemented screening and treatment or referral for treatment programs, the majority are evaluating how to best address this recommendation and no standard approach for screening and treatment currently exists. Further, guidelines are not yet available with respect to resources that may be used to effectively screen and treat these disorders in trauma survivors, as well as who is going to bear the costs. The purpose of this review is: 1) to evaluate the current state of the literature regarding evidence-based screens for PTSD and depression in the hospitalized trauma patient, and 2) summarize the literature to date regarding the treatments that have empirical support in treating PTSD and depression acutely after injury. This review also includes structural and funding information regarding existing post-injury mental health programs. Screening of injured patients and timely intervention to prevent or treat PTSD and depression could substantially improve health outcomes and improve quality of life for this high-risk population. LEVEL OF EVIDENCE: Review, level IV.

[1]  S. Fakhry,et al.  Implementation and Utility of an Automated Text Messaging System to Facilitate Symptom Self-Monitoring and Identify Risk for Post-traumatic Stress Disorder and Depression in Trauma Center Patients. , 2019, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[2]  L. Nelson,et al.  Detecting PTSD in a traumatically injured population: The diagnostic utility of the PTSD Checklist for DSM‐5 , 2018, Depression and anxiety.

[3]  K. Ruggiero,et al.  Peritraumatic distress predicts depression in traumatically injured patients admitted to a Level I trauma center. , 2018, General hospital psychiatry.

[4]  M. Kramer,et al.  Do screening and a randomized brief intervention at a Level 1 trauma center impact acute stress reactions to prevent later development of posttraumatic stress disorder? , 2018, The journal of trauma and acute care surgery.

[5]  K. Brasel,et al.  Six-month follow-up of the injured trauma survivor screen: Clinical implications and future directions , 2018, The journal of trauma and acute care surgery.

[6]  B. Gabbe,et al.  Early psychological interventions for posttraumatic stress, depression and anxiety after traumatic injury: A systematic review and meta-analysis. , 2018, Clinical psychology review.

[7]  K. Ruggiero,et al.  The Peritraumatic Distress Inventory: Factor structure and predictive validity in traumatically injured patients admitted through a Level I trauma center. , 2018, Journal of anxiety disorders.

[8]  T. Laursen,et al.  Survival and health related quality of life after severe trauma - a 15 years follow up study. , 2017, Injury.

[9]  K. Ruggiero,et al.  An Automated Text-Messaging System to Monitor Emotional Recovery After Pediatric Injury: Pilot Feasibility Study. , 2017, Psychiatric services.

[10]  D. Spain,et al.  Development and preliminary performance of a risk factor screen to predict posttraumatic psychological disorder after trauma exposure. , 2017, General hospital psychiatry.

[11]  J. Ford,et al.  Complementing SBIRT for Alcohol Misuse with SBIRT for Trauma: A Feasibility Study , 2017, Implementing the Grand Challenge of Reducing and Preventing Alcohol Misuse and its Consequences.

[12]  Peter W. Tuerk,et al.  A non-inferiority trial of Prolonged Exposure for posttraumatic stress disorder: In person versus home-based telehealth. , 2017, Behaviour research and therapy.

[13]  L. Shek,et al.  Screening for Depression in Hospitalized Medical Patients , 2017, Journal of hospital medicine.

[14]  J. Davies How Voting and Consensus Created the Diagnostic and Statistical Manual of Mental Disorders (DSM-III) , 2017, Anthropology & medicine.

[15]  S. Wall,et al.  Traumatic injury in the United States: In-patient epidemiology 2000-2011. , 2016, Injury.

[16]  Peter W. Tuerk,et al.  BEHAVIORAL ACTIVATION AND THERAPEUTIC EXPOSURE FOR POSTTRAUMATIC STRESS DISORDER: A NONINFERIORITY TRIAL OF TREATMENT DELIVERED IN PERSON VERSUS HOME‐BASED TELEHEALTH , 2016, Depression and anxiety.

[17]  Jim Mintz,et al.  Psychometric analysis of the PTSD Checklist-5 (PCL-5) among treatment-seeking military service members. , 2016, Psychological assessment.

[18]  David A. Chambers,et al.  An effectiveness-implementation hybrid trial study protocol targeting posttraumatic stress disorder and comorbidity , 2015, Implementation Science.

[19]  Tracy K. Witte,et al.  The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5): Development and Initial Psychometric Evaluation. , 2015, Journal of traumatic stress.

[20]  Erik G Van Eaton,et al.  Technology-Enhanced Stepped Collaborative Care Targeting Posttraumatic Stress Disorder and Comorbidity After Injury: A Randomized Controlled Trial. , 2015, Journal of traumatic stress.

[21]  G. Zarkin,et al.  The Impact of a Mandated Trauma Center Alcohol Intervention on Readmission and Cost per Readmission in Arizona , 2015, Medical care.

[22]  Erica K. Yuen,et al.  Randomized Controlled Trial of Home-Based Telehealth Versus In-Person Prolonged Exposure for Combat-Related PTSD in Veterans: Preliminary Results. , 2015, Journal of clinical psychology.

[23]  A. Statnikov,et al.  Quantitative forecasting of PTSD from early trauma responses: a Machine Learning application. , 2014, Journal of psychiatric research.

[24]  Deborah J Couillard,et al.  A feasibility pilot study on the use of text messages to track PTSD symptoms after a traumatic injury. , 2014, General hospital psychiatry.

[25]  Mark B. Powers,et al.  Predictors of PTSD symptoms in adults admitted to a Level I trauma center: a prospective analysis. , 2014, Journal of anxiety disorders.

[26]  W. Katon,et al.  The development of a population-based automated screening procedure for PTSD in acutely injured hospitalized trauma survivors. , 2013, General hospital psychiatry.

[27]  W. Katon,et al.  A Randomized Stepped Care Intervention Trial Targeting Posttraumatic Stress Disorder for Surgically Hospitalized Injury Survivors , 2013, Annals of surgery.

[28]  R. Lyons,et al.  Evaluating Time Points for Measuring Recovery After Major Trauma in Adults , 2013, Annals of surgery.

[29]  K. Ressler,et al.  Early Intervention May Prevent the Development of Posttraumatic Stress Disorder: A Randomized Pilot Civilian Study with Modified Prolonged Exposure , 2012, Biological Psychiatry.

[30]  T. Osler,et al.  Outcomes of adult trauma patients admitted to trauma centers in Pennsylvania, 2000-2009. , 2012, Archives of surgery.

[31]  Michelle Dougherty,et al.  The 10 security domains (updated). , 2012, Journal of AHIMA.

[32]  R. Bryant,et al.  Stepped early psychological intervention for posttraumatic stress disorder, other anxiety disorders, and depression following serious injury. , 2012, Journal of traumatic stress.

[33]  M. Delatycki The ethics of screening for disease , 2012, Pathology.

[34]  F. Winston,et al.  Predicting the future development of depression or PTSD after injury. , 2011, General hospital psychiatry.

[35]  R. Bryant Acute stress disorder as a predictor of posttraumatic stress disorder: a systematic review. , 2011, The Journal of clinical psychiatry.

[36]  Daniel O Scharfstein,et al.  The value of trauma center care. , 2010, The Journal of trauma.

[37]  E. Mackenzie,et al.  One-year treatment costs of trauma care in the USA , 2010, Expert review of pharmacoeconomics & outcomes research.

[38]  D. Silove,et al.  The psychiatric sequelae of traumatic injury. , 2010, The American journal of psychiatry.

[39]  Peter W. Tuerk,et al.  A pilot study of prolonged exposure therapy for posttraumatic stress disorder delivered via telehealth technology. , 2010, Journal of traumatic stress.

[40]  G. Bonanno,et al.  Psychopathology and resilience following traumatic injury: a latent growth mixture model analysis. , 2010, Rehabilitation psychology.

[41]  M. Compton,et al.  Screening adults for depression in primary care: A position statement of the American College of Preventive Medicine. , 2009, The Journal of family practice.

[42]  A. Mykletun,et al.  Levels of anxiety and depression as predictors of mortality: the HUNT study , 2009, British Journal of Psychiatry.

[43]  D. Silove,et al.  A predictive screening index for posttraumatic stress disorder and depression following traumatic injury. , 2008, Journal of consulting and clinical psychology.

[44]  Frederick P Rivara,et al.  A National US Study of Posttraumatic Stress Disorder, Depression, and Work and Functional Outcomes After Hospitalization for Traumatic Injury , 2008, Annals of surgery.

[45]  G. Jurkovich,et al.  Behavioral Activation as an Early Intervention for Posttraumatic Stress Disorder and Depression Among Physically Injured Trauma Survivors , 2007 .

[46]  C. Hewitt,et al.  Screening for Depression in Medical Settings with the Patient Health Questionnaire (PHQ): A Diagnostic Meta-Analysis , 2007, Journal of General Internal Medicine.

[47]  S. Galea,et al.  Comparison of two widely used PTSD-screening instruments: implications for public mental health planning. , 2006, Journal of traumatic stress.

[48]  J. Weigelt,et al.  Predicting quality of life six months after traumatic injury. , 2005, The Journal of trauma.

[49]  B. Ebel,et al.  Alcohol interventions for trauma patients treated in emergency departments and hospitals: a cost benefit analysis. , 2005 .

[50]  J. Guelfi,et al.  Validation de la version française de l'inventaire de détresse péritraumatique , 2005 .

[51]  A. Nathens,et al.  Development of trauma systems and effect on outcomes after injury , 2004, The Lancet.

[52]  W. Katon,et al.  A randomized effectiveness trial of stepped collaborative care for acutely injured trauma survivors. , 2004, Archives of general psychiatry.

[53]  G. Ramirez,et al.  Identifying depression in primary care: a literature synthesis of case-finding instruments. , 2002, General hospital psychiatry.

[54]  G. Jurkovich,et al.  Posttraumatic stress, problem drinking, and functional outcomes after injury. , 2002, Archives of surgery.

[55]  R. Spitzer,et al.  The PHQ-9 , 2001, Journal of General Internal Medicine.

[56]  Suzanne R. Best,et al.  The Peritraumatic Distress Inventory: a proposed measure of PTSD criterion A2. , 2001, The American journal of psychiatry.

[57]  K Kroenke,et al.  Validation and Utility of the Patient Health Questionnaire in Diagnosing Mental Disorders in 1003 General Hospital Spanish Inpatients , 2001, Psychosomatic medicine.

[58]  R. Kravitz,et al.  Patients with recognized psychiatric disorders in trauma surgery: incidence, inpatient length of stay, and cost. , 2000, The Journal of trauma.

[59]  R. Spitzer,et al.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. , 1999, JAMA.

[60]  A. Vickers,et al.  COMPARISON OF AN ORDINAL AND A CONTINUOUS OUTCOME MEASURE OF MUSCLE SORENESS , 1999, International Journal of Technology Assessment in Health Care.

[61]  W. Long,et al.  Outcome from injury: general health, work status, and satisfaction 12 months after trauma. , 1999, The Journal of trauma.

[62]  R. Kessler,et al.  The economic burden of anxiety disorders in the 1990s. , 1999, The Journal of clinical psychiatry.

[63]  J P Anderson,et al.  Outcome after major trauma: discharge and 6-month follow-up results from the Trauma Recovery Project. , 1998, The Journal of trauma.

[64]  D. Hoyt,et al.  Outcome after major trauma: 12-month and 18-month follow-up results from the Trauma Recovery Project. , 1998 .

[65]  E. Hickling,et al.  Psychiatric Morbidity Associated with Motor Vehicle Accidents , 1995, The Journal of nervous and mental disease.

[66]  P M Fayers,et al.  Measuring and analysing quality of life in cancer clinical trials: a review. , 1983, Statistics in medicine.

[67]  K. Brasel,et al.  Utility of the injured trauma survivor screen to predict PTSD and depression during hospital admission , 2017, The journal of trauma and acute care surgery.

[68]  Jasmine Adela Mutang,et al.  Psychometric evaluation of Malay version of Peritraumatic Distress Inventory (M-PDI) and Peritraumatic Dissociative experiences Questionnaire (M-PDEQ) using the sample of flood victims in Kuching, Sarawak, Malaysia , 2017 .

[69]  Joshua C. Hunt Predicting Postraumatic Stress Disorder in Single-Incident Trauma Survivors with an Acute Injury , 2015 .

[70]  A. Warren,et al.  Rehabilitation psychology's role in the level I trauma center. , 2014, Journal of trauma nursing : the official journal of the Society of Trauma Nurses.

[71]  S. Kanba,et al.  Reliability and validity of the Japanese version of the Peritraumatic Distress Inventory. , 2009, General hospital psychiatry.

[72]  J. Guelfi,et al.  [Validation of the Peritraumatic Distress Inventory's French translation]. , 2005, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[73]  Catharyn T. Liverman,et al.  Reducing the burden of injury : advancing prevention and treatment , 1999 .

[74]  D. Hoyt,et al.  Outcome after major trauma: 12-month and 18-month follow-up results from the Trauma Recovery Project. , 1999, The Journal of trauma.