论文信息 - Discovery of (R)-8-(1-(3,5-difluorophenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (AZD8186): a potent and selective inhibitor of PI3Kβ and PI3Kδ for the treatment of PTEN-deficient cancers. - 字舞流文

Discovery of (R)-8-(1-(3,5-difluorophenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (AZD8186): a potent and selective inhibitor of PI3Kβ and PI3Kδ for the treatment of PTEN-deficient cancers.

S. Green | B. Barlaam | S. Degorce | M. Maudet | R. Morgentin | A. Peru | P. Plé | S. Cosulich | Urs J Hancox | M. Fitzek | Lara Ward | C. Lambert-van der Brempt | M. Pasquet | J. Lohmann | Nicolas Warin | Twana Saleh | M. Vautier | Michael J A Walker