Relapsing panniculitis (Weber-Christian disease); review of literature and report of a case including treatment with cortisone.

A CASE OF relapsing panniculitis (Weber-Christian) disease has been extensively studied for approximately 21 months, from the inception of the disease until the death of the patient. In this paper is outlined the course of the illness with the various studies conducted in an effort to ascertain the cause and the possible lines of therapy which may aid in the management of patients with this disease. The disease occurs in various grades of severity, from that of a relatively benign course to the overwhelming picture of toxicity manifested in the present case. The illness is termed relapsing, febrile, nodular, nonsuppurative panniculitis. The second word of this title was added by Christian1in 1928 to the original descriptive designation by Weber,2who accurately reported the disease in 1925. Previously, Pfeiffer3in 1892 and Gilchrist and Ketron4in 1916 had described the clinical and histopathological features of this

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