Poor Physical Capacity Combined With High Body Fat Percentage as an Independent Risk Factor for Incident Hypertension in Chinese Suburb-Dwelling Older Adults

Background This study examined the effects of poor physical capacity and high body fat percentage (BF%) on the incidence of hypertension in Chinese suburb-dwelling older adults. Methods This study was conducted on 368 Chinese suburb-dwelling participants aged ≥ 60 years without hypertension (mean age: 66.74 ± 5.59 years, 48.9% men). Poor physical capacity is defined by the Asian Working Group for Sarcopenia (AWGS) criteria as grip strength < 26 kg for men and < 18 kg for women or walking speed <0.8 m/s. High BF% was defined as values that are greater than the upper tertile for BF% as stratified by sex. The outcome was the incidence of hypertension. Results Overall, 5.7% of subjects had both poor physical capacity and high BF%. After the average follow-up duration of 2 years, the incidence of hypertension was 39.7%, and those experiencing both poor physical capacity and high BF% had the highest incidence (81.0%). After multivariate adjustments, the incidence of hypertension was associated with the combination of poor physical capacity and high BF% [odds ratio (OR) = 6.43, 95% CI = 1.91–21.64] but not solely with poor physical capacity (OR = 1.11, 95% CI = 0.55–2.25) or only high BF% (OR = 1.37, 95% CI = 0.80–2.34). Conclusion The combination of poor physical capacity and high BF% can significantly increase the incidence of hypertension in Chinese suburb-dwelling older adults. For hypertension prevention, ideally, we should strive toward decreasing body fat mass while simultaneously improving physical capacity.

[1]  J. Kasprzak,et al.  A report from the American Heart Association Scientific Sessions 2021 , 2022, Folia Cardiologica.

[2]  L. Ferrucci,et al.  International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management , 2018, The journal of nutrition, health & aging.

[3]  S. Polyzos,et al.  Sarcopenic obesity , 2018, Hormones.

[4]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[5]  K. Niu,et al.  The increased risk of sarcopenia in patients with cardiovascular risk factors in Suburb-Dwelling older Chinese using the AWGS definition , 2017, Scientific Reports.

[6]  J. L. F. Santos,et al.  Dynapenic obesity as an associated factor to lipid and glucose metabolism disorders and metabolic syndrome in older adults - Findings from SABE Study. , 2017, Clinical nutrition.

[7]  F. Pires,et al.  Hypertension and functional capacities in community-dwelling older women: a cross-sectional study , 2017, Blood pressure.

[8]  S. Kritchevsky,et al.  Body Composition and Physical Function in Older Adults with Various Comorbidities , 2017, Innovation in aging.

[9]  A. Vigano,et al.  New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss , 2016, Journal of cachexia, sarcopenia and muscle.

[10]  L. Ferrucci,et al.  Replication study of the vitamin D receptor (VDR) genotype association with skeletal muscle traits and sarcopenia , 2016, Aging Clinical and Experimental Research.

[11]  K. Niu,et al.  Incidence, risk factors, and the protective effect of high body mass index against sarcopenia in suburb-dwelling elderly Chinese populations , 2016, The journal of nutrition, health & aging.

[12]  Mark D. Huffman,et al.  Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association , 2016, Circulation.

[13]  Farzaneh A. Sorond,et al.  Aging, the Central Nervous System, and Mobility in Older Adults: Neural Mechanisms of Mobility Impairment. , 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

[14]  S. Inoue,et al.  Recent genetic discoveries in osteoporosis, sarcopenia and obesity. , 2015, Endocrine journal.

[15]  T. Miura,et al.  The combination of abdominal obesity and high-sensitivity C-reactive protein predicts new-onset hypertension in the general Japanese population: the Tanno–Sobetsu study , 2015, Hypertension Research.

[16]  Chia-Ing Li,et al.  Comparison of height‐ and weight‐adjusted sarcopenia in a Taiwanese metropolitan older population , 2015, Geriatrics & gerontology international.

[17]  Yixiong Liang,et al.  Poor Lower Extremity Function Was Associated with Pre-Diabetes and Diabetes in Older Chinese People , 2014, PloS one.

[18]  Sheldon Cohen,et al.  Negative social interactions and incident hypertension among older adults. , 2014, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[19]  P. D. de Leeuw,et al.  Treatment of Hypertension in the Oldest Old: A Critical Role for Frailty? , 2014, Hypertension.

[20]  Jackson T. Wright,et al.  2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). , 2014, JAMA.

[21]  L. Peng,et al.  Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia. , 2014, Journal of the American Medical Directors Association.

[22]  Kyungdo Han,et al.  Sarcopenia as a Determinant of Blood Pressure in Older Koreans: Findings from the Korea National Health and Nutrition Examination Surveys (KNHANES) 2008–2010 , 2014, PloS one.

[23]  F. Irie,et al.  Association of Alcohol Consumption With Incident Hypertension Among Middle-Aged and Older Japanese Population: The Ibarakai Prefectural Health Study (IPHS) , 2014, Hypertension.

[24]  J. G. Lee,et al.  Sarcopenic obesity as an independent risk factor of hypertension. , 2013, Journal of the American Society of Hypertension : JASH.

[25]  Juan Xu,et al.  Impact of baseline prehypertension on cardiovascular events and all-cause mortality in the general population: a meta-analysis of prospective cohort studies. , 2013, International journal of cardiology.

[26]  Jeroen J. Bax,et al.  2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). , 2013, European heart journal.

[27]  L. Fratiglioni,et al.  Association of Cardiovascular Burden with Mobility Limitation among Elderly People: A Population-Based Study , 2013, PloS one.

[28]  Y. Yi,et al.  Body fat percentage is associated with cardiometabolic dysregulation in BMI-defined normal weight subjects. , 2012, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[29]  L. Kuller,et al.  High Blood Pressure Accelerates Gait Slowing in Well‐Functioning Older Adults over 18‐Years of Follow‐Up , 2011, Journal of the American Geriatrics Society.

[30]  Rebecca Hardy,et al.  Objective measures of physical capability and subsequent health: a systematic review , 2010, Age and ageing.

[31]  G. Salem,et al.  American College of Sports Medicine position stand. Exercise and physical activity for older adults. , 2009, Medicine and science in sports and exercise.

[32]  Michael Böhm,et al.  2013 ESH/ESC Guidelines for the management of arterial hypertension , 2007, Blood pressure.

[33]  S. Leeder,et al.  A population based study , 1993, The Medical journal of Australia.

[34]  Chia-Wen Lu,et al.  A cross sectional study , 2019 .

[35]  K. Goel,et al.  The concept of normal weight obesity. , 2014, Progress in cardiovascular diseases.

[36]  K. He,et al.  Meta-analysis of prospective cohort studies , 2011 .