The role of cytochrome P-450 forms in 2-aminoanthracene and benz[α]pyrene mutagenesis

[1]  P. Thomas,et al.  Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. , 1979, The Journal of biological chemistry.

[2]  U. Muller-eberhard,et al.  Identification of the major cytochrome P-450 form transplacentally induced in neonatal rabbits by 3,3,7,8-tetrachlorodibenzo-p-dioxin. , 1978, The Journal of biological chemistry.

[3]  F. Guengerich.  Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest. , 1977, The Journal of biological chemistry.

[4]  U. Muller-eberhard,et al.  Purification of the major cytochrome P-450 of liver microsomes from rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). , 1977, Biochemical and biophysical research communications.

[5]  U. Muller-eberhard,et al.  Multiple forms of cytochrome P-450: resolution and purification of rabbit liver aryl hydrocarbon hydroxylase. , 1977, Biochemical and biophysical research communications.

[6]  U. Muller-eberhard,et al.  Resolution of two forms of cytochrome P-450 from liver microsomes of rabbit treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. , 1977, The Journal of biological chemistry.

[7]  M. J. Coon,et al.  Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450. , 1976, The Journal of biological chemistry.

[8]  D. Jerina,et al.  Mutagenicity and cytotoxicity of benzo(a)pyrene arene oxides, phenols, quinones, and dihydrodiols in bacterial and mammalian cells. , 1976, Cancer research.

[9]  A. Y. Lu,et al.  Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes. , 1976, The Journal of biological chemistry.

[10]  A. Y. Lu,et al.  Separation, purification, and properties of multiple forms of cytochrome P-450 from the liver microsomes of phenobarbital-treated mice. , 1976, The Journal of biological chemistry.

[11]  R. Philpot,et al.  Separation and purification of two forms of hepatic cytochrome P-450 from untreated rabbits. , 1976, Molecular pharmacology.

[12]  D. Jerina,et al.  High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene. , 1976, Biochemical and biophysical research communications.

[13]  Y. Imai,et al.  Purification of a substrate complex of cytochrome P-450 from liver microsomes of 3-methylcholanthrene-treated rabbits. , 1976, Biochemical and biophysical research communications.

[14]  B. Ames,et al.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. , 1975, Mutation research.

[15]  A. Y. Lu,et al.  Highly purified cytochrome P-448 and P=450 from rat liver microsomes. , 1975, Biochemical and biophysical research communications.

[16]  M. J. Coon,et al.  Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms. , 1975, The Journal of biological chemistry.

[17]  R. Mayer,et al.  Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. , 1974, Drug metabolism and disposition: the biological fate of chemicals.

[18]  Y. Imai,et al.  A gel-electrophoretically homogeneous preparation of cytochrome P-450 from liver microsomes of phenobarbital-pretreated rabbits. , 1974, Biochemical and biophysical research communications.

[19]  D. Nebert,et al.  Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assay and properties of induced enzyme. , 1968, The Journal of biological chemistry.

[20]  A. Conney.  Pharmacological implications of microsomal enzyme induction. , 1967, Pharmacological reviews.

[21]  S. Orrenius.  ON THE MECHANISM OF DRUG HYDROXYLATION IN RAT LIVER MICROSOMES , 1965, The Journal of cell biology.