Clathrin and associated assembly and disassembly proteins.

PERSPECTIVES AND SUMMARY. . ....... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415 CLATHRIN . . . . . ...... . . . . . . . . .. . . . . .. .... .. . . . . . . . . ....... . .. . . . . . . . . . . . . . . . . . . . . . ...... . . . . 4 1 7 Clathrin Heavy Chains 417 Clathrin Light Chains 417 Clathrin Trimer/Triskelion...... ......... ...... ........ . . . . . . . . ....... . . . . . . . . . 419 APs: ASSEMBLY PROTEINS/ADAPTOR PROTEINS/ASSOCIATED PROTEINS.... 423 AP-2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423 AP-I and AP1801AP-3 . 426 AP Activities 427 AP-Membrane Interactions 429 UNCOATING ATPase/Hsc70. . . . ...... . . . . . 431 Uncoating ATPase is Hsc70 431 Functions of the Hsc70lUncoating ATPase 433