Pancuronium bromide induced joint contractures in the newborn

aetiology. Our experience is similar to that reported by others. 3 If the condition is infective in origin one might expect, as in acute vertebral osteomyelitis, to find extensive local bony destruction, a more chronic course, and positive blood, biopsy or aspiration cultures. In the two patients reported by Shah and Miller where an organism was isolated from blood cultures, we agree that antibiotic treatment was indicated. We would not agree that broad spectrum antibiotics should be offered to all cases. In the absence of proved bacteriological infection bed rest alone has been shown to be adequate treatment.1 3 Controversy will continue until a control study of antibiotic treatment is performed.