Premature white matter aging in patients with right mesial temporal lobe epilepsy: A machine learning approach based on diffusion MRI data

Highlights • A brain age prediction model was developed based on diffusion MRI data.• Patients with right MTLE exhibited older brain age than those with left MTLE.• Predicted age difference (PAD) was correlated with seizure frequency in right MTLE.• Right uncinate fasciculus had highest contribution to the observed PAD in right MTLE.

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