Combined Influence of Genetic Polymorphism and DNA Methylation on ABCB1 Expression and Function in Healthy Chinese Males
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[1] Y. Li,et al. Interindividual epigenetic variation in ABCB1 promoter and its relationship with ABCB1 expression and function in healthy Chinese subjects. , 2015, British journal of clinical pharmacology.
[2] Paolo Garagnani,et al. The epigenetic side of human adaptation: hypotheses, evidences and theories , 2015, Annals of human biology.
[3] L. Davidson,et al. Noninvasive molecular fingerprinting of host–microbiome interactions in neonates , 2014, FEBS letters.
[4] M. Gottesman,et al. MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer. , 2014, Cancer research.
[5] A. Nader,et al. Suitability of digoxin as a P‐glycoprotein probe: Implications of other transporters on sensitivity and specificity , 2014, Journal of clinical pharmacology.
[6] T. Marquès-Bonet,et al. DNA methylation contributes to natural human variation , 2013, Genome research.
[7] H. Gréen,et al. ABCB1 gene polymorphisms are associated with suicide in forensic autopsies , 2013, Pharmacogenetics and genomics.
[8] K. Oka,et al. Decitabine, a DNA methyltransferase inhibitor, reduces P-glycoprotein mRNA and protein expressions and increases drug sensitivity in drug-resistant MOLT4 and Jurkat cell lines. , 2012, Anticancer research.
[9] Jingbo Wang,et al. An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics , 2011, The Pharmacogenomics Journal.
[10] I. Ieiri,et al. Interindividual differences in placental expression of the SLC22A2 (OCT2) gene: relationship to epigenetic variations in the 5'-upstream regulatory region. , 2011, Journal of pharmaceutical sciences.
[11] R. Altman,et al. Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). , 2011, Pharmacogenetics and genomics.
[12] Hein Putter,et al. Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[13] C. Sapienza,et al. Inter- and Intra-Individual Variation in Allele-Specific DNA Methylation and Gene Expression in Children Conceived using Assisted Reproductive Technology , 2010, PLoS genetics.
[14] Joseph D. Ma,et al. Evaluation of In Vivo P-Glycoprotein Phenotyping Probes , 2010, Clinical pharmacokinetics.
[15] T. Aas,et al. DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response , 2010, Molecular Cancer.
[16] Achim Tresch,et al. Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns , 2010, Nucleic acids research.
[17] J. Sprowl,et al. The temporal relationship between ABCB1 promoter hypomethylation, ABCB1 expression and acquisition of drug resistance , 2010, The Pharmacogenomics Journal.
[18] Gang-yi Liu,et al. Therapeutic monitoring of serum digoxin for patients with heart failure using a rapid LC-MS/MS method. , 2010, Clinical biochemistry.
[19] Rong Liu,et al. Correlation between MDR1 methylation status in the promoter region and MDR1 genetic polymorphism in 194 healthy Chinese Han subjects. , 2008, Pharmacogenomics.
[20] Huande Li,et al. Impact of MDR1 Haplotypes Derived from C1236T, G2677T/A and C3435T on the Pharmacokinetics of Single-Dose Oral Digoxin in Healthy Chinese Volunteers , 2008, Pharmacology.
[21] S. Yagi,et al. Epigenetics: the DNA methylation profile of tissue-dependent and differentially methylated regions in cells. , 2008, Placenta.
[22] M. Pirmohamed,et al. ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research , 2007, The Pharmacogenomics Journal.
[23] Michel Eichelbaum,et al. Interindividual variability of canalicular ATP‐binding‐cassette (ABC)–transporter expression in human liver , 2006, Hepatology.
[24] B. Meibohm,et al. G2677T and C3435T Genotype and Haplotype Are Associated With Hepatic ABCB1 (MDR1) Expression , 2006, Journal of clinical pharmacology.
[25] J. Zalcberg,et al. Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs , 2005, Oncogene.
[26] Andrew D. Johnson,et al. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability , 2005, Pharmacogenetics and genomics.
[27] A. M. George,et al. The ABC transporter structure and mechanism: perspectives on recent research , 2004, Cellular and Molecular Life Sciences CMLS.
[28] R. Ho,et al. (Section A: Molecular, Structural, and Cellular Biology of Drug Transporters) The Role of MDR1 Genetic Polymorphisms in Interindividual Variability in P-glycoprotein Expression and Function , 2004 .
[29] K. Budde,et al. MDR1 Haplotypes Do Not Affect the Steady‐State Pharmacokinetics of Cyclosporine in Renal Transplant Patients , 2003, Journal of clinical pharmacology.
[30] Werner Siegmund,et al. The effects of the human MDR1 genotype on the expression of duodenal P‐glycoprotein and disposition of the probe drug talinolol , 2002, Clinical pharmacology and therapeutics.
[31] G. Kessie,et al. Markers of Inflammation and Lineage on Exfoliated Colonic Cells In Pediatric Inflammatory Bowel Disease. , 2011, Journal of gastrointestinal & digestive system.
[32] H. Glaeser. Importance of P-glycoprotein for drug-drug interactions. , 2011, Handbook of experimental pharmacology.
[33] F. Wang,et al. Up-regulation of ABCB1/P-glycoprotein by escaping promoter hypermethylation indicates poor prognosis in hematologic malignancy patients with and without bone marrow transplantation. , 2011, Leukemia research.
[34] R. Ho,et al. The role of MDR1 genetic polymorphisms in interindividual variability in P-glycoprotein expression and function. , 2004, Current drug metabolism.