Androgens up-regulate atherosclerosis-related genes in macrophages from males but not females: molecular insights into gender differences in atherosclerosis.

[1]  Ailsa E Gebbie,et al.  Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women's Health Initiative Randomized Controlled Trial. Writing Group for the Women's Health Initiative Investigators. JAMA 2002; 288(3): 321-333 , 2002, Journal of Family Planning and Reproductive Health Care.

[2]  Charles Kooperberg,et al.  Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. , 2002, JAMA.

[3]  H. Showell,et al.  Leukotriene B4 Receptor Antagonism Reduces Monocytic Foam Cells in Mice , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[4]  J. Stallone,et al.  Androgen-receptor defect abolishes sex differences in nitric oxide and reactivity to vasopressin in rat aorta. , 2001, Journal of applied physiology.

[5]  P. Libby,et al.  CD40 Signaling and Plaque Instability , 2001, Circulation research.

[6]  D. Celermajer,et al.  Sex-related differences in the regulation of macrophage cholesterol metabolism , 2001, Current opinion in lipidology.

[7]  C. Holm,et al.  Expression, Activity, and Subcellular Localization of Testicular Hormone-Sensitive Lipase During Postnatal Development in the Guinea Pig1 , 2001, Biology of reproduction.

[8]  L. Young,et al.  Vasopressin (V1a) Receptor Binding, mRNA Expression and Transcriptional Regulation by Androgen in the Syrian Hamster Brain , 2000, Journal of neuroendocrinology.

[9]  Peng Huang,et al.  Superoxide dismutase as a target for the selective killing of cancer cells , 2000, Nature.

[10]  David Handelsman,et al.  Androgen receptor expression is greater in macrophages from male than from female donors. A sex difference with implications for atherogenesis. , 2000, Circulation.

[11]  D. Celermajer,et al.  Estrogen and progesterone reduce lipid accumulation in human monocyte-derived macrophages: a sex-specific effect. , 1999, Circulation.

[12]  David Handelsman,et al.  Androgen exposure increases human monocyte adhesion to vascular endothelium and endothelial cell expression of vascular cell adhesion molecule-1. , 1999, Circulation.

[13]  M. Karkkainen,et al.  Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cells , 1999, Molecular and Cellular Endocrinology.

[14]  S. Sordello,et al.  Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens. , 1998, Biochemical and biophysical research communications.

[15]  E. Vittinghoff,et al.  Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. , 1998, JAMA.

[16]  C. Ludlam,et al.  The effects of low‐dose testosterone treatment on lipid metabolism, clotting factors and ultrasonographic ovarian morphology in women , 1998, Clinical endocrinology.

[17]  H. Burger,et al.  Should women be treated with testosterone? , 1998, Clinical endocrinology.

[18]  T. B. Morrison,et al.  Quantification of low-copy transcripts by continuous SYBR Green I monitoring during amplification. , 1998, BioTechniques.

[19]  P. Halushka,et al.  Gender-related differences in androgen regulation of thromboxane A2 receptors in rat aortic smooth-muscle cells. , 1997, Journal of cardiovascular pharmacology.

[20]  A. Sulli,et al.  Androgen and estrogen receptors are present in primary cultures of human synovial macrophages. , 1996, The Journal of clinical endocrinology and metabolism.

[21]  I. Tabas.  The stimulation of the cholesterol esterification pathway by atherogenic lipoproteins in macrophages , 1995, Current opinion in lipidology.

[22]  R. Anderson,et al.  Haemostatic Effects of Supraphysiological Levels of Testosterone in Normal Men , 1995, Thrombosis and Haemostasis.

[23]  S. Eto,et al.  Androgen receptors, 5 alpha-reductase activity and androgen-dependent proliferation of vascular smooth muscle cells , 1994, The Journal of Steroid Biochemistry and Molecular Biology.

[24]  R. Dean,et al.  Human macrophage-mediated oxidation of low-density lipoprotein is delayed and independent of superoxide production. , 1994, The Biochemical journal.

[25]  H. Tunstall-Pedoe,et al.  Myocardial Infarction and Coronary Deaths in the World Health Organization MONICA Project: Registration Procedures, Event Rates, and Case‐Fatality Rates in 38 Populations From 21 Countries in Four Continents , 1994, Circulation.

[26]  W D Wagner,et al.  A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. , 1994, Circulation.

[27]  R. Ross.  The pathogenesis of atherosclerosis: a perspective for the 1990s , 1993, Nature.

[28]  J. Glatz,et al.  Modulation of fatty-acid-binding protein content of rat heart and skeletal muscle by endurance training and testosterone treatment , 1992, Pflügers Archiv.

[29]  R. Daynes,et al.  Dihydrotestosterone exerts a depressive influence on the production of interleukin-4 (IL-4), IL-5, and gamma-interferon, but not IL-2 by activated murine T cells. , 1991, Blood.

[30]  Y. Hochberg.  A sharper Bonferroni procedure for multiple tests of significance , 1988 .

[31]  V. Toscano,et al.  Circulating dihydrotestosterone may not reflect peripheral formation. , 1987, The Journal of clinical investigation.

[32]  Alice R. Johnson,et al.  Steroid 5α-reductase activity in endothelial cells from human umbilical cord vessels , 1987 .

[33]  P. Greenspan,et al.  Retroendocytosis of low density lipoprotein. Effect of lysosomal inhibitors on the release of undegraded 125I-low density lipoprotein of altered composition from skin fibroblasts in culture. , 1984, The Journal of biological chemistry.

[34]  G. Toews,et al.  Androstenedione metabolism in human alveolar macrophages. , 1983, The Journal of clinical endocrinology and metabolism.

[35]  E. Barrett-Connor,et al.  The sex differential in mortality from all causes and ischemic heart disease. , 1983, American journal of epidemiology.

[36]  R. Ross,et al.  The pathogenesis of atherosclerosis (first of two parts). , 1976, The New England journal of medicine.

[37]  J. Wilson,et al.  Dihydrotestosterone in prostatic hypertrophy. I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man. , 1970, The Journal of clinical investigation.

[38]  S. Sordello,et al.  Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens. , 1998, Biochemical and biophysical research communications.

[39]  S. Bulun,et al.  Aromatase expression in health and disease. , 1997, Recent progress in hormone research.

[40]  A. Johnson,et al.  Steroid 5 alpha-reductase activity in endothelial cells from human umbilical cord vessels. , 1987, Journal of steroid biochemistry.

[41]  M. Brown,et al.  Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. , 1983, Methods in enzymology.