ToxoDB: an integrated Toxoplasma gondii database resource

ToxoDB (http://ToxoDB.org) is a genome and functional genomic database for the protozoan parasite Toxoplasma gondii. It incorporates the sequence and annotation of the T. gondii ME49 strain, as well as genome sequences for the GT1, VEG and RH (Chr Ia, Chr Ib) strains. Sequence information is integrated with various other genomic-scale data, including community annotation, ESTs, gene expression and proteomics data. ToxoDB has matured significantly since its initial release. Here we outline the numerous updates with respect to the data and increased functionality available on the website.

[1]  J. Shenai,et al.  Infectious Diseases of the Fetus and Newborn Infant , 2001, Journal of Perinatology.

[2]  Val Tannen,et al.  K2/Kleisli and GUS: Experiments in integrated access to genomic data sources , 2001, IBM Syst. J..

[3]  S. Lewis,et al.  The generic genome browser: a building block for a model organism system database. , 2002, Genome research.

[4]  Philippa Rhodes,et al.  ApiDB: integrated resources for the apicomplexan bioinformatics resource center , 2006, Nucleic Acids Res..

[5]  Li Li,et al.  PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data , 2003, Nucleic Acids Res..

[6]  Ian T. Paulsen,et al.  Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii , 2005, Nucleic acids research.

[7]  Steve Wilson,et al.  The Immune Epitope Database and Analysis Resource: From Vision to Blueprint , 2005, PLoS biology.

[8]  J. Klein,et al.  Infectious Diseases of the Fetus and Newborn Infant , 1983 .

[9]  Feng Chen,et al.  OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups , 2005, Nucleic Acids Res..

[10]  Robert D. Finn,et al.  New developments in the InterPro database , 2007, Nucleic Acids Res..

[11]  Aaron J Mackey,et al.  The transcriptome of Toxoplasma gondii , 2005, BMC Biology.

[12]  Peter J Bradley,et al.  Proteomic Analysis of Rhoptry Organelles Reveals Many Novel Constituents for Host-Parasite Interactions in Toxoplasma gondii* , 2005, Journal of Biological Chemistry.

[13]  Li Li,et al.  ToxoDB: accessing the Toxoplasma gondii genome , 2003, Nucleic Acids Res..

[14]  David S Roos,et al.  Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii , 2006, PLoS pathogens.

[15]  B. Luft,et al.  Toxoplasmic encephalitis in AIDS. , 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.