Sleep patterns and total mortality: a 12-year follow-up study in Japan.

A population-based cohort study was conducted to assess the relationship between total mortality and self-reported sleep patterns as regards not only to sleep duration but also subjective sleep quality. A total of 5,322 inhabitants in Gifu Prefecture, Japan, completed a self-administered questionnaire on health status and lifestyles including habitual sleep patterns, and were followed-up for an average of 11.9 years. Relative risks were computed by using Cox proportional hazards models. Both longer and shorter sleep, compared to 7-8 hour-sleep, was related to significantly increased risk of total mortality in males (relative risk [RR] for > or = 10 hours = 1.94, and RR for < 7 hour = 1.90), but not in females. Females complaining of poor awakening state experienced a higher mortality risk compared to those who woke up normally (RR: 1.97). Males who usually fell asleep easily showed a marginally lower mortality risk compared to those who fell asleep normally (RR: 0.70). Female users of sleeping pills were at an elevated risk (RR: 1.89). These findings were almost unchanged after adjustment for sleep duration and other confounders. Poor self-reported quality of sleep seemed to be associated with an increased risk of mortality independently of sleep duration.

[1]  T. Gislason,et al.  Sleep disturbances in a young adult population: can gender differences be explained by differences in psychological status? , 1997, Sleep.

[2]  P. Enright,et al.  Sleep Disturbance, Psychosocial Correlates, and Cardiovascular Disease in 5201 Older Adults: The Cardiovascular Health Study , 1997, Journal of the American Geriatrics Society.

[3]  D J Foley,et al.  Sleep complaints among elderly persons: an epidemiologic study of three communities. , 1995, Sleep.

[4]  J. Horne,et al.  Gender- and age-related differences in sleep determined by home-recorded sleep logs and actimetry from 400 adults. , 1995, Sleep.

[5]  G. P. Rozál,et al.  Psychiatric status and 9-year mortality data in the New Haven Epidemiologic Catchment Area Study. , 1994, The American journal of psychiatry.

[6]  J. Yesavage,et al.  Depression as a confounding variable in the estimation of habitual sleep time. , 1993, Journal of clinical psychology.

[7]  D. Bliwise,et al.  Sleep in normal aging and dementia. , 1993, Sleep.

[8]  S. Quan,et al.  Risk factors associated with complaints of insomnia in a general adult population. Influence of previous complaints of insomnia. , 1992, Archives of internal medicine.

[9]  K. Morgan.  Hypnotics, Sleep, and Mortality in Elderly People , 1992, Journal of the American Geriatrics Society.

[10]  S. Weyerer,et al.  Prevalence and treatment of insomnia in the community: results from the Upper Bavarian Field Study. , 1991, Sleep.

[11]  C. Guilleminault,et al.  Insomnia and use of hypnotics: study of a French population. , 1991, Sleep.

[12]  Daniel J Buysse,et al.  Electroencephalographic sleep in the healthy "old old": a comparison with the "young old" in visually scored and automated measures. , 1991, Journal of gerontology.

[13]  Ian W. M. Smith,et al.  Sleep patterns in rural elders: demographic, health, and psychobehavioral correlates. , 1991, Journal of clinical epidemiology.

[14]  J. Krueger.  Somnogenic activity of immune response modifiers. , 1990, Trends in pharmacological sciences.

[15]  A. Rechtschaffen,et al.  Sleep deprivation in the rat: X. Integration and discussion of the findings. , 2002, Sleep.

[16]  B. O’Donnell,et al.  Troublesome and Disruptive Behaviors in Dementia , 1988, Journal of the American Geriatrics Society.

[17]  J. Rodin,et al.  A longitudinal study of depressed mood and sleep disturbances in elderly adults. , 1988, Journal of gerontology.

[18]  T. Erkinjuntti,et al.  Sleep apnea in multiinfarct dementia and Alzheimer's disease. , 1987, Sleep.

[19]  M. Dunn,et al.  Breathing pattern abnormalities and arterial oxygen desaturation during sleep in the congestive heart failure syndrome. Improvement following medical therapy. , 1987, Chest.

[20]  D. Kupfer,et al.  Empirical note: self-report versus recorded sleep in healthy seniors. , 1987, Psychophysiology.

[21]  S. Quan,et al.  Prevalence of reported sleep disturbances in a general adult population and their relationship to obstructive airways diseases. , 1987, Chest.

[22]  H. Moldofsky,et al.  Sleep and morning pain in primary osteoarthritis. , 1987, The Journal of rheumatology.

[23]  W. Mendelson.  Neuroendocrinology and Sleep , 1987 .

[24]  H Lechner,et al.  Sleep alterations in ischemic stroke. , 1986, European neurology.

[25]  E. Uhlenhuth,et al.  Insomnia and its treatment. Prevalence and correlates. , 1985, Archives of general psychiatry.

[26]  L. Berkman,et al.  Mortality risk associated with sleeping patterns among adults. , 1983, Sleep.

[27]  A. Rechtschaffen,et al.  Physiological correlates of prolonged sleep deprivation in rats. , 1983, Science.

[28]  J. Kaprio,et al.  Sleep disorders in relation to coronary heart disease. , 2009, Acta medica Scandinavica. Supplementum.

[29]  E. Bixler,et al.  Prevalence of sleep disorders in the Los Angeles metropolitan area. , 1979, The American journal of psychiatry.

[30]  E. C. Hammond,et al.  Short and long sleep and sleeping pills. Is increased mortality associated? , 1979, Archives of general psychiatry.

[31]  L. Cohen.  A Controlled Study of Trancopal in Sleep Disturbances Due to Rheumatic Disease , 1978, The Journal of international medical research.

[32]  M Jinks,et al.  Insomnia and its treatment. , 1976, Journal of the American Pharmaceutical Association.

[33]  E. C. Hammond,et al.  Coronary heart disease, stroke, and aortic aneurysm. , 1969, Archives of environmental health.

[34]  E. C. Hammond,et al.  SOME PRELIMINARY FINDINGS ON PHYSICAL COMPLAINTS FROM A PROSPECTIVE STUDY OF 1,064,004 MEN AND WOMEN. , 1964, American journal of public health and the nation's health.

[35]  Nathan Mantel,et al.  Chi-square tests with one degree of freedom , 1963 .

[36]  D.,et al.  Regression Models and Life-Tables , 2022 .