Asbestos: scientific developments and implications for public policy.

Asbestos is a commercial term for a group of fibrous minerals often associated with the development of pulmonary interstitial fibrosis (asbestosis), lung cancer, and malignant mesothelioma in occupationally exposed individuals. The pathogenicity of different forms of asbestos varies--long, thin amphibole fibers are most pathogenic, particularly in the induction of mesothelioma. Available data do not support the concept that low-level exposure to asbestos is a health hazard in buildings and schools. The concentration of asbestos fibers in air, type of asbestos, and size of fibers must be considered in evaluation of potential health risks.

[1]  B. Mossman,et al.  Asbestos-related diseases. , 1989, The New England journal of medicine.

[2]  B. Mossman,et al.  Sensitivity of hamster tracheal epithelial cells to asbestiform minerals modulated by serum and by transforming growth factor beta 1. , 1989, Cancer research.

[3]  M. Newhouse,et al.  A mortality study of workers manufacturing friction materials: 1941-86. , 1989, British journal of industrial medicine.

[4]  A. D. McDonald,et al.  Respiratory cancer in chrysotile textile and mining industries: exposure inferences from lung analysis. , 1989, British journal of industrial medicine.

[5]  D. Kohtz,et al.  Asbestos fibers mediate transformation of monkey cells by exogenous plasmid DNA. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[6]  J. Mcdonald,et al.  Low level exposure to asbestos: is there a cancer risk? , 1988, British journal of industrial medicine.

[7]  S. Knuutila,et al.  Nonrandom chromosomal abnormalities in malignant pleural mesothelioma. , 1988, Cancer genetics and cytogenetics.

[8]  Y. P. Lu,et al.  Use of the orthogonal design method to study the synergistic effects of asbestos fibres and 12-O-tetradecanoylphorbol-13-acetate (TPA) in the BALB/3T3 cell transformation system. , 1988, Mutagenesis.

[9]  T. H. van der Kwast,et al.  Expression of c-sis (PDGF B-chain) and PDGF A-chain genes in ten human malignant mesothelioma cell lines derived from primary and metastatic tumors. , 1988, Oncogene.

[10]  S. Mikalsen,et al.  Morphological transformation of Syrian hamster embryo cells induced by mineral fibres and the alleged enhancement of benzo[a]pyrene. , 1988, Carcinogenesis.

[11]  B. Corrin,et al.  Correlation between fibre content of the lung and disease in east London asbestos factory workers. , 1988, British journal of industrial medicine.

[12]  B. Mossman,et al.  Mechanisms of induction of ornithine decarboxylase activity in tracheal epithelial cells by asbestiform minerals. , 1988, Cancer research.

[13]  D. Edelman Exposure to asbestos and the risk of gastrointestinal cancer: a reassessment. , 1988, British journal of industrial medicine.

[14]  E. Gabrielson,et al.  Comparison of production of transforming growth factor-beta and platelet-derived growth factor by normal human mesothelial cells and mesothelioma cell lines. , 1987, Cancer research.

[15]  M. Nebut,et al.  Pleural carcinogenic potency of mineral fibers (asbestos, attapulgite) and their cytotoxicity on cultured cells. , 1987, Journal of the National Cancer Institute.

[16]  J. L. Macdonald,et al.  Acute injury and regeneration of the mesothelium in response to asbestos fibers. , 1987, The American journal of pathology.

[17]  S. Cordier,et al.  Epidemiologic investigation of respiratory effects related to environmental exposure to asbestos inside insulated buildings. , 1987, Archives of environmental health.

[18]  S. Weitzman,et al.  Asbestos catalyzes the formation of the 6-oxobenzo[a]pyrene radical from 6-hydroxybenzo[a]pyrene. , 1987, Archives of biochemistry and biophysics.

[19]  P. Enterline,et al.  Geographic patterns for pleural mesothelioma deaths in the United States, 1968-81. , 1987, Journal of the National Cancer Institute.

[20]  D. Coffin,et al.  Metaphase and anaphase analysis of V79 cells exposed to erionite, UICC chrysotile and UICC crocidolite. , 1987, Carcinogenesis.

[21]  B. Mossman,et al.  Generation of superoxide (O2-.) from alveolar macrophages exposed to asbestiform and nonfibrous particles. , 1987, Cancer research.

[22]  Y Y Hammad,et al.  Mortality of workers employed in two asbestos cement manufacturing plants. , 1987, British journal of industrial medicine.

[23]  M. Jaurand,et al.  A Scanning and Transmission Electron Microscopic Study , 2007 .

[24]  M. Gardner,et al.  Follow up study of workers manufacturing chrysotile asbestos cement products. , 1986, British journal of industrial medicine.

[25]  M Corn,et al.  Asbestos and disease: an industrial hygienist's perspective. , 1986, American Industrial Hygiene Association journal.

[26]  Y. Nishizuka Studies and perspectives of protein kinase C. , 1986, Science.

[27]  Gary R. Grotendorst,et al.  Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages. , 1986, The Journal of clinical investigation.

[28]  A. D. McDonald,et al.  Cohort study of mortality of vermiculite miners exposed to tremolite. , 1986, British journal of industrial medicine.

[29]  B. Wiggs,et al.  Cigarette smoke increases the penetration of asbestos fibers into airway walls. , 1986, The American journal of pathology.

[30]  M. Jaurand,et al.  Chromosomal changes induced by chrysotile fibres or benzo-3,4-pyrene in rat pleural mesothelial cells. , 1986, Mutation research.

[31]  B. Mossman,et al.  Alteration of superoxide dismutase activity in tracheal epithelial cells by asbestos and inhibition of cytotoxicity by antioxidants. , 1986, Laboratory investigation; a journal of technical methods and pathology.

[32]  I. Lemaire,et al.  Alveolar macrophage stimulation of lung fibroblast growth in asbestos-induced pulmonary fibrosis. , 1986, The American journal of pathology.

[33]  M. Travisano,et al.  Correlation of in vitro genotoxicity and oncogenicity induced by radiation and asbestos fibres. , 1985, British Journal of Cancer.

[34]  C Hogstedt,et al.  Lung cancer among asbestos cement workers. A Swedish cohort study and a review. , 1985, British journal of industrial medicine.

[35]  C. Harris,et al.  Asbestos-associated chromosomal changes in human mesothelial cells. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[36]  R. J. Hill,et al.  Erionite exposure and mesotheliomas in rats. , 1985, British Journal of Cancer.

[37]  M. Jaurand,et al.  In vitro transformation of rat pleural mesothelial cells by chrysotile fibres and/or benzo[a]pyrene. , 1985, Carcinogenesis.

[38]  J. Barrett,et al.  Induction by asbestos fibers of anaphase abnormalities: mechanism for aneuploidy induction and possibly carcinogenesis. , 1985, Carcinogenesis.

[39]  M. Newhouse,et al.  Combined effect of asbestos and smoking on mortality from lung cancer and mesothelioma in factory workers. , 1985, British journal of industrial medicine.

[40]  M. Oshimura,et al.  Correlation of asbestos-induced cytogenetic effects with cell transformation of Syrian hamster embryo cells in culture. , 1984, Cancer research.

[41]  J. Barrett,et al.  Dependence of asbestos- and mineral dust-induced transformation of mammalian cells in culture on fiber dimension. , 1984, Cancer research.

[42]  A. D. McDonald,et al.  Dust exposure and mortality in an American factory using chrysotile, amosite, and crocidolite in mainly textile manufacture. , 1983, British journal of industrial medicine.

[43]  A. D. McDonald,et al.  Dust exposure and mortality in an American chrysotile textile plant. , 1983, British journal of industrial medicine.

[44]  A. Eastman,et al.  Influence of asbestos on the uptake of benzo(a)pyrene and DNA alkylation in hamster tracheal epithelial cells. , 1983, Cancer research.

[45]  R. Brown,et al.  The influence of asbestos dust on the oncogenic transformation of C3H10T 1/2 cells. , 1983, Cancer letters.

[46]  M. Newhouse,et al.  Mortality of workers manufacturing friction materials using asbestos. , 1983, British journal of industrial medicine.

[47]  C. Harris,et al.  Cellular ingestion, toxic effects, and lesions observed in human bronchial epithelial tissue and cells cultured with asbestos and glass fibers , 1982, International journal of cancer.

[48]  F. Pooley,et al.  Mesotheliomas and asbestos type in asbestos textile workers: a study of lung contents. , 1982, British medical journal.

[49]  P C Elwood,et al.  Further follow-up study of workers from an asbestos cement factory. , 1982, British journal of industrial medicine.

[50]  E. C. Hammond,et al.  Latency of asbestos disease among insulation workers in the United States and Canada , 1980, Cancer.

[51]  P. Nettesheim,et al.  Two-Stage Carcinogenesis Studies With Asbestos in Fischer 344 Rats , 1980 .

[52]  I J Selikoff,et al.  ASBESTOS EXPOSURE, CIGARETTE SMOKING AND DEATH RATES * , 1979, Annals of the New York Academy of Sciences.

[53]  J. Bignon,et al.  FRENCH MESOTHELIOMA REGISTER * † , 1979, Annals of the New York Academy of Sciences.

[54]  S. L. Huang,et al.  Amosite, chrysotile and crocidolite asbestos are mutagenic in Chinese hamster lung cells. , 1979, Mutation research.

[55]  M Chamberlain,et al.  Asbestos and glass fibres in bacterial mutation tests. , 1977, Mutation research.

[56]  R. Lilis,et al.  HOUSEHOLD‐CONTACT ASBESTOS NEOPLASTIC RISK * , 1976, Annals of the New York Academy of Sciences.

[57]  G. Berry,et al.  The Effects of the Inhalation of Asbestos in Rats , 1974, British Journal of Cancer.

[58]  M. Stanton,et al.  Mechanisms of mesothelioma induction with asbestos and fibrous glass. , 1972, Journal of the National Cancer Institute.

[59]  B. Gee,et al.  Action on asbestos. , 1971, The New England journal of medicine.

[60]  G. Sluis-Cremer,et al.  ASBESTOSIS IN SOUTH AFRICA—CERTAIN GEOGRAPHICAL AND ENVIRONMENTAL CONSIDERATIONS , 1965, Annals of the New York Academy of Sciences.

[61]  J. Wagner,et al.  Diffuse Pleural Mesothelioma and Asbestos Exposure in the North Western Cape Province , 1960, British journal of industrial medicine.

[62]  M. Shelby The genetic toxicity of human carcinogens and its implications. , 1988, Mutation research.

[63]  J. DiPaolo,et al.  Nonrandom chromosome alterations in human malignant mesothelioma. , 1988, Cancer research.

[64]  B. Mossman,et al.  Approaches to prevention of asbestos-induced lung disease using polyethylene glycol (PEG)-conjugated catalase. , 1986, Journal of free radicals in biology & medicine.

[65]  G. Burdett,et al.  Airborne asbestos concentrations in buildings. , 1986, The Annals of occupational hygiene.

[66]  H. Weill,et al.  Asbestos as a public health risk: disease and policy. , 1986, Annual review of public health.

[67]  S. Weitzman,et al.  Asbestos-catalysed lipid peroxidation and its inhibition by desferroxamine. , 1985, The Biochemical journal.

[68]  S. Weitzman,et al.  Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxide. , 1984, Archives of biochemistry and biophysics.

[69]  J. DiPaolo,et al.  Asbestos and benzo(a)pyrene synergism in the transformation of Syrian hamster embryo cells. , 1983, Pharmacology.

[70]  H. Silberman Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain. , 1983, Pharmacology.

[71]  M. Symons,et al.  Exposures and mortality among chrysotile asbestos workers. Part II: mortality. , 1983, American journal of industrial medicine.

[72]  F. Pooley,et al.  A pathological and mineralogical study of asbestos-related deaths in the United Kingdom in 1977. , 1982, The Annals of occupational hygiene.