Metastatic Thymoma with Myasthenia Gra vis

A 29-year-old male developed myasthenia gravis 29 months after resection of a “benign” mediastinal thymoma. Metastatic thymoma was found in the pleura 45 months after the initial surgical resection. Combination chemotherapy with cyclophosphamide and doxorubicin produced a complete remission of the metastatic thymoma which has continued for 13 months. Concurrently, there has been a marked increase in neuromuscular function. Cancer 50:419-422. 1982.

[1]  A. Paccagnella,et al.  Chemotherapy of invasive thymoma. , 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2]  J. Pagani,et al.  Thymoma metastatic to bone. , 1979, Journal of the National Medical Association.

[3]  N. Vick,et al.  Invasive thymoma responsive to oral corticosteroids. , 1978, Cancer treatment reports.

[4]  A. Gerein,et al.  Thymoma: a ten year review. , 1978, American journal of surgery.

[5]  R. Marks,et al.  Radiation therapy control of nine patients with malignant thymoma , 1978, Cancer.

[6]  S. Kalnicki,et al.  The management of malignant thymoma with radiation therapy , 1977 .

[7]  J. Eggleston,et al.  Thymoma. A clinical and pathological study of 65 cases , 1976 .

[8]  N. Martini,et al.  Thymomas: Clinicopathologic features, therapy, and prognosis , 1974, Cancer.

[9]  J. Gutterman,et al.  Clinical evaluation of toxic effects of cis-diamminedichloroplatinum (NSC-119875)--phase I clinical study. , 1973, Cancer chemotherapy reports.

[10]  C. Bull Thymoma , 1932, Proceedings of the Royal Society of Medicine.

[11]  Jeffrey M. Liebmann,et al.  a ten year review , 1998 .

[12]  Masako Kobayashi,et al.  Myasthenia gravis and invasive thymoma. A 20-year experience. , 1993, European neurology.

[13]  I. Jaffrey,et al.  Response to maytansine in a patient with malignant thymoma. , 1980, Cancer treatment reports.

[14]  W. Simpson,et al.  Combination chemotherapy in invasive thymoma role of COPP. , 1980, Cancer.

[15]  J. Parker,et al.  Cerebral metastasis from a malignant thymoma. , 1978, Surgical neurology.