Is agmatine a novel neurotransmitter in brain?

[1]  A. Yates,et al.  Stimulus-secretion coupling of arginine-induced insulin release: comparison between the cationic amino acid and its methyl ester. , 2000, Endocrine.

[2]  D. Reis,et al.  Characterization of Arginine Decarboxylase in Rat Brain and Liver , 2000, Journal of neurochemistry.

[3]  R. Blantz,et al.  An emerging role for agmatine. , 1999, Kidney international.

[4]  M. Moskowitz,et al.  Pathobiology of ischaemic stroke: an integrated view , 1999, Trends in Neurosciences.

[5]  G. Olmos,et al.  Protection by imidazol(ine) drugs and agmatine of glutamate‐induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor , 1999, British journal of pharmacology.

[6]  D. Reis,et al.  Anti‐Proliferative and Anti‐Inflammatory Actions of Imidazoline Agents: Are Imidazoline Receptors Involved? , 1999, Annals of the New York Academy of Sciences.

[7]  I. Musgrave,et al.  Novel Targets and Techniques in Imidazoline Receptor Research a , 1999, Annals of the New York Academy of Sciences.

[8]  C. A. Ramsden,et al.  Imidazolines and Pancreatic Hormone Secretion a , 1999, Annals of the New York Academy of Sciences.

[9]  D. Reis,et al.  Agmatine selectively blocks the N-methyl-D-aspartate subclass of glutamate receptor channels in rat hippocampal neurons. , 1999, The Journal of pharmacology and experimental therapeutics.

[10]  M. P. Dillon,et al.  'Seeing through a glass darkly': casting light on imidazoline 'I' sites. , 1998, Trends in pharmacological sciences.

[11]  D. Reis,et al.  Agmatine containing axon terminals in rat hippocampus form synapses on pyramidal cells , 1998, Neuroscience Letters.

[12]  D. Reis,et al.  Regional localization of agmatine in the rat brain: an immunocytochemical study , 1998, Brain Research.

[13]  D. Reis,et al.  Metabolism of agmatine in macrophages: modulation by lipopolysaccharide and inhibitory cytokines. , 1998, The Biochemical journal.

[14]  D. Reis,et al.  Imidazoline receptor proteins are regulated in platelet-precursor MEG-01 cells by agonists and antagonists. , 1998, Journal of psychiatric research.

[15]  D. Reis,et al.  Uptake of Agmatine into Rat Brain Synaptosomes: Possible Role of Cation Channels , 1997, Journal of neurochemistry.

[16]  İ. Uzbay,et al.  Inhibitory effect of agmatine on naloxone-precipitated abstinence syndrome in morphine dependent rats. , 1997, Life sciences.

[17]  J. Piletz,et al.  Determination of agmatine in brain and plasma using high-performance liquid chromatography with fluorescence detection. , 1997, Journal of chromatography. B, Biomedical sciences and applications.

[18]  D. Reis,et al.  Agmatine, an endogenous modulator of noradrenergic neurotransmission in the rat tail artery , 1996, British journal of pharmacology.

[19]  D. Reis,et al.  Agmatinase Activity in Rat Brain: A Metabolic Pathway for the Degradation of Agmatine , 1996, Journal of neurochemistry.

[20]  J. Rabey,et al.  Arginine and ornithine decarboxylation in rodent brain: coincidental changes during development and after ischemia , 1996, Neuroscience Letters.

[21]  G. Wilcox,et al.  A nitric oxide synthesis inhibitor (L-NAME) reduces licking behavior and Fos-labeling in the spinal cord of rats during formalin-induced inflammation , 1996, PAIN®.

[22]  D. Reis,et al.  Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine. , 1996, The Biochemical journal.

[23]  G. Bennett,et al.  Molecular characterization of adiY, a regulatory gene which affects expression of the biodegradative acid-induced arginine decarboxylase gene (adiA) of Escherichia coli. , 1996, Microbiology.

[24]  D. Reis,et al.  Imidazoline receptors and agmatine in blood vessels: a novel system inhibiting vascular smooth muscle proliferation. , 1996, The Journal of pharmacology and experimental therapeutics.

[25]  G. Pasternak,et al.  Modulation of opioid analgesia by agmatine. , 1996, European journal of pharmacology.

[26]  P. Insel,et al.  Agmatine, a bioactive metabolite of arginine. Production, degradation, and functional effects in the kidney of the rat. , 1996, The Journal of clinical investigation.

[27]  D. Reis,et al.  Agmatine (decarboxylated arginine) is synthesized and stored in astrocytes , 1995, Neuroreport.

[28]  S. Kalra,et al.  Agmatine, a novel hypothalamic amine, stimulates pituitary luteinizing hormone release in vivo and hypothalamic luteinizing hormone-releasing hormone release in vitro , 1995, Neuroscience Letters.

[29]  D. Reis,et al.  Agmatine, the bacterial amine, is widely distributed in mammalian tissues. , 1995, Life sciences.

[30]  S. Klahr,et al.  Partial cloning and characterization of an arginine decarboxylase in the kidney. , 1995, Kidney international.

[31]  F. Tesson,et al.  Localization of I2-Imidazoline Binding Sites on Monoamine Oxidases (*) , 1995, The Journal of Biological Chemistry.

[32]  P. Ernsberger,et al.  Comparison of the properties of agmatine and endogenous clonidine-displacing substance at imidazoline and alpha-2 adrenergic receptors. , 1995, The Journal of pharmacology and experimental therapeutics.

[33]  D. Reis,et al.  An antibody to agmatine localizes the amine in bovine adrenal chromaffin cells , 1995, Neuroscience Letters.

[34]  D. Ash,et al.  Rat liver arginase: kinetic mechanism, alternate substrates, and inhibitors. , 1994, Archives of biochemistry and biophysics.

[35]  D. Reis,et al.  Agmatine: an endogenous clonidine-displacing substance in the brain. , 1994, Science.

[36]  R. Malmberg,et al.  Arginine decarboxylase of oats is activated by enzymatic cleavage into two polypeptides. , 1994, The Journal of biological chemistry.

[37]  F. Tesson,et al.  L 5 ‐ IMIDAZOLINE‐GUANIDINIUM RECEPTIVE SITE (IGRS): MITOCHONDRIAL DISTRIBUTION AND REGULATION PROPERTIES , 1992, Fundamental & clinical pharmacology.

[38]  G. Gilad,et al.  Polyamine uptake, binding and release in rat brain. , 1991, European journal of pharmacology.

[39]  N. Morgan,et al.  Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels. , 1990, European journal of pharmacology.

[40]  R. Loring Agmatine acts as an antagonist of neuronal nicotinic receptors , 1990, British journal of pharmacology.

[41]  W. Malaisse,et al.  Stimulus-secretion coupling of arginine-induced insulin release. Insulinotropic action of agmatine. , 1989, Biochemical pharmacology.

[42]  D. Alkon,et al.  Autoradiographic measurement of tritiated agmatine as an indicator of physiologic activity inHermissenda visual and vestibular neurons , 1986, Journal of neurocytology.

[43]  S. Boyle,et al.  Purification and properties of agmatine ureohydrolyase, a putrescine biosynthetic enzyme in Escherichia coli , 1986, Journal of bacteriology.

[44]  W. H. Wu,et al.  Biosynthetic arginine decarboxylase from Escherichia coli. Purification and properties. , 1973, The Journal of biological chemistry.

[45]  D. Reis,et al.  Agmatine: a novel neurotransmitter? , 1998, Advances in pharmacology.

[46]  D. Reis,et al.  Imidazoline receptors and their endogenous ligands. , 1996, Annual review of pharmacology and toxicology.

[47]  B. Pfeiffer,et al.  Insulin-like partial effects of agmatine derivatives in adipocytes. , 1980, Hoppe-Seyler´s Zeitschrift für physiologische Chemie.