Cemented versus cementless megaprosthesis in proximal femur metastatic disease: A systematic review

The proximal femur is the long bone most commonly affected by metastatic disease. There are many treatment options, such as hip megaprostheses. A topic still widely debated in literature is the use of cemented or uncemented megaprostheses in this kind of patients. The purpose of this review is to examine both these surgical options to understand which of them should be preferred in metastatic patients. Twelve articles were finally included in the review. Eight authors used cemented mega - prostheses, two cementless megaprostheses and two authors used both techniques. Better functional outcomes and lower infection rates were found in cementless mega - prostheses. More studies have to be performed to choose the better technique and improve patients’ quality of life.

[1]  R. Bitsch,et al.  En-Bloc Resection of Metastases of the Proximal Femur and Reconstruction by Modular Arthroplasty is Not Only Justified in Patients with a Curative Treatment Option—An Observational Study of a Consecutive Series of 45 Patients , 2020, Journal of clinical medicine.

[2]  M. Sanguinetti,et al.  Antifungal properties of silver coating on tumour endoprostheses: an in vitro study. , 2019, European review for medical and pharmacological sciences.

[3]  G. Maccauro,et al.  Functional outcome and multidimensional evaluation of patients with Mutars® reconstructions post lower limb tumor resection and rehabilitation: preliminary results. , 2019, Journal of biological regulators and homeostatic agents.

[4]  A. Grasso,et al.  Hip megaprosthesis in oncological surgery: open questions. , 2019, Journal of biological regulators and homeostatic agents.

[5]  N. Maffulli,et al.  Single dose cefazolin is safe and effective for pre-operative prophylaxis in orthopaedic oncology. , 2018, Journal of biological regulators and homeostatic agents.

[6]  P. Ruggieri,et al.  Treatment of pathologic fractures of the proximal femur. , 2018, Injury.

[7]  G. Guzik Oncological and functional results after surgical treatment of bone metastases at the proximal femur , 2018, BMC Surgery.

[8]  G. Maccauro,et al.  Soft tissue adhesion patterns over Trevira tube on modular endoprosthesis for malignant bone tumours: an in vitro study. , 2017, Journal of biological regulators and homeostatic agents.

[9]  A. Piccioli,et al.  Infective complications in tumour endoprostheses implanted after pathological fracture of the limbs. , 2016, Injury.

[10]  G. Maccauro,et al.  Silver-Coated Hip Megaprosthesis in Oncological Limb Savage Surgery , 2016, BioMed research international.

[11]  M. Ferrone,et al.  Complications After Surgical Management of Proximal Femoral Metastasis: A Retrospective Study of 417 Patients , 2016, The Journal of the American Academy of Orthopaedic Surgeons.

[12]  A. Piccioli,et al.  QUALITY OF LIFE FOLLOWING SURGICAL TREATMENT OF LOWER LIMB METASTASES IN LONG BONE. , 2015, Journal of biological regulators and homeostatic agents.

[13]  A. Piccioli,et al.  Impending fracture: A difficult diagnosis. , 2014, Injury.

[14]  Pietro Ruggieri,et al.  Management of long bone metastases: recommendations from the Italian Orthopaedic Society bone metastasis study group , 2014, Expert review of anticancer therapy.

[15]  G. Maccauro,et al.  A rare case of iliac crest metastasis from acinic cell carcinoma of parotid gland , 2014, World Journal of Surgical Oncology.

[16]  C. Josten,et al.  Safety aspects in surgical treatment of pathological fractures of the proximal femur – modular endoprosthetic replacement vs. intramedullary nailing , 2013, Patient Safety in Surgery.

[17]  A. Mavrogenis,et al.  Cemented versus cementless endoprostheses for lower limb salvage surgery. , 2013, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

[18]  A. Mavrogenis,et al.  Survival analysis of patients with femoral metastases , 2012, Journal of surgical oncology.

[19]  P. Böhm,et al.  The use of a femoral revision stem in the treatment of primary or secondary bone tumours of the proximal femur: a prospective study of 31 cases. , 2010, The Journal of bone and joint surgery. British volume.

[20]  G. Letson,et al.  Endoprosthetic proximal femur replacement: metastatic versus primary tumors. , 2009, Surgical oncology.

[21]  N J Harper,et al.  Bone cement implantation syndrome. , 2009, British journal of anaesthesia.

[22]  T. Damron,et al.  Adverse Clinical Events During Cemented Long-Stem Femoral Arthroplasty , 2002, Clinical orthopaedics and related research.