Frequency of Chlamydia trachomatis in Endocervical Samples of Women Referred to a Gynecology Hospital in Qazvin, Iran

Results: Out of the 240 female participants, 184 (76.7%) were symptomatic and 56 (23.3%) were asymptomatic cases. The mean age of cases was 37.1 ± 0.9 years. Twenty (8.3%) of the 240 samples were diagnosed as Chlamydia positive according to PCR results. The prevalence of asymptomatic C. trachomatis infections was six (10.7%), while there were 14 (7.6%) in symptomatic cases. Although positive PCR results have shown in women with vaginosis (7.1%), abortion (5.1%), premature birth and low birth weight below 2.5 kg (7.7%) but the chi-square test did not indicate a significant relationship between positive PCR test results and these symptoms. Conclusions: The results of this study showed that there was a high prevalence of C. trachomatis infection among both symptomatic and asymptomatic women. Therefore, a screening test for C. trachomatis infection is recommended for all women who refer to the genitourinary medicine clinic. Screening programs are important for cost effectiveness calculations of C. trachomatis infections especially in asymptomatic cases.

[1]  Elizabeth A Torrone,et al.  Prevalence of Chlamydia trachomatis Genital Infection Among Persons Aged 14–39 Years — United States, 2007–2012 , 2014, MMWR. Morbidity and mortality weekly report.

[2]  L. Abu-Raddad,et al.  Prevalence of Chlamydia trachomatis infection in the general population of women in Qatar , 2013, Sexually Transmitted Infections.

[3]  T. Read,et al.  A Multiplexed Microfluidic PCR Assay for Sensitive and Specific Point-of-Care Detection of Chlamydia trachomatis , 2012, PloS one.

[4]  A. Znazen,et al.  Chlamydia trachomatis genovar distribution in clinical urogenital specimens from Tunisian patients: high prevalence of C. trachomatis genovar E and mixed infections , 2012, BMC Infectious Diseases.

[5]  C. Cuffini,et al.  Molecular Epidemiology of Genital Chlamydia T rachomatis Infection in Asymptomatic Adolescent-Young People , 2012 .

[6]  V. Vullo,et al.  Epidemiology of Chlamydia trachomatis endocervical infection in a previously unscreened population in Rome, Italy, 2000 to 2009. , 2012, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[7]  E. Hiltunen-Back,et al.  Chlamydia trachomatis Genotypes and the Swedish New Variant among Urogenital Chlamydia trachomatis Strains in Finland , 2011, Infectious diseases in obstetrics and gynecology.

[8]  S. Morré,et al.  Genotyping of Chlamydia trachomatis strains from culture and clinical samples using an ompA-based DNA microarray assay. , 2011, Molecular and Cellular Probes.

[9]  Bin Yang,et al.  The prevalence and distribution of Chlamydia trachomatis genotypes among sexually transmitted disease clinic patients in Guangzhou, China, 2005-2008. , 2010, Japanese journal of infectious diseases.

[10]  W. Mcfarland,et al.  HIV/AIDS in the Middle East and North Africa: new study methods, results, and implications for prevention and care , 2010, AIDS.

[11]  David P. Wilson,et al.  Characterizing the HIV/AIDS Epidemic in the Middle East and North Africa: Time for Strategic Action , 2010 .

[12]  M. Postma,et al.  Epidemiology of Chlamydia trachomatis infection in women and the cost-effectiveness of screening. , 2010, Human reproduction update.

[13]  E. Sakurai,et al.  Prevalence and risk factors for Chlamydia trachomatis infection in adolescent females and young women in central Brazil , 2006, European Journal of Clinical Microbiology and Infectious Diseases.

[14]  Mellisa L. Theodore,et al.  Comparison of Three Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis in Urine Specimens , 2004, Journal of Clinical Microbiology.

[15]  P. Mårdh Tubal factor infertility, with special regard to chlamydial salpingitis , 2004, Current opinion in infectious diseases.

[16]  J. Peipert,et al.  Genital Chlamydial Infections , 2003 .

[17]  J. Paavonen,et al.  The accuracy and efficacy of screening tests for Chlamydia trachomatis: a systematic review. , 2002, Journal of medical microbiology.

[18]  L. Ottosson,et al.  Chlamydia trachomatis PCR (Cobas Amplicor) in women: endocervical specimen transported in a specimen of urine versus endocervical and urethral specimens in 2-SP medium versus urine specimen only , 2000, International journal of STD & AIDS.

[19]  Ellen Jo Baron,et al.  Manual of clinical microbiology , 1975 .

[20]  E. Baron,et al.  Chlamydia and Chlamydophila. , 2006 .

[21]  H. Goudarzi,et al.  Detection of Chlamydia trachomatis from Urine Specimens by PCR in Women with Cervicitis , 2005 .

[22]  Jeffrey F Peipert,et al.  Clinical practice. Genital chlamydial infections. , 2003, The New England journal of medicine.