stage-specific expansion and harbor genetic and epigenetic alterations Stem and progenitor cells in myelodysplastic syndromes show aberrant
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C. Steidl | J. Greally | A. Verma | C. McMahon | C. Montagna | J. Boultwood | A. Pellagatti | T. Vogler | Laura Barreyro | T. Bhagat | L. Zhou | A. List | C. Heuck | R. Tamari | C. Schinke | B. Hilda | S. Ben-Neriah
[1] A. Feinberg,et al. Regulated Noise in the Epigenetic Landscape of Development and Disease , 2012, Cell.
[2] M. J. Ruiz,et al. Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor. , 2011, Blood.
[3] E. Estey,et al. Coalesced multicentric analysis of 2,351 patients with myelodysplastic syndromes indicates an underestimation of poor-risk cytogenetics of myelodysplastic syndromes in the international prognostic scoring system. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[4] Hua Yu,et al. STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma. , 2011, Cancer research.
[5] P. Vyas,et al. Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia. , 2011, Cancer cell.
[6] S. Orkin,et al. Dnmt3a silences hematopoietic stem cell self-renewal , 2011, Nature Genetics.
[7] P. Woll,et al. Persistent malignant stem cells in del(5q) myelodysplasia in remission. , 2010, The New England journal of medicine.
[8] S. Orkin,et al. DNA methylation in adult stem cells: New insights into self-renewal , 2010, Epigenetics.
[9] M Cazzola,et al. Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells , 2010, Leukemia.
[10] M. Kawahara,et al. Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome. , 2009, Blood.
[11] Lucy Skrabanek,et al. MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. , 2009, Blood.
[12] S. Orkin,et al. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. , 2009, Cell stem cell.
[13] Reid F. Thompson,et al. High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers , 2009, Nucleic acids research.
[14] Valeria Santini,et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. , 2009, The Lancet. Oncology.
[15] C. O'keefe,et al. Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. , 2009, Blood.
[16] J. McNamara. Cancer Stem Cells , 2007, Methods in Molecular Biology.
[17] J. Gabrilove,et al. A Phase I Trial of the Epigenetic Modulators Vorinostat, in Combination with Azacitidine (azaC) in Patients with the Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML): A Study of the New York Cancer Consortium , 2008 .
[18] M. Bitzer,et al. Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS. , 2008, Blood.
[19] Quan Chen,et al. An analytical pipeline for genomic representations used for cytosine methylation studies , 2008, Bioinform..
[20] K. Anderson,et al. The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes. , 2007, Blood.
[21] R. Verhaak,et al. A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia. , 2007, The Journal of clinical investigation.
[22] W. Guida,et al. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity , 2007, Proceedings of the National Academy of Sciences.
[23] A. Verma,et al. From bloodjournal.hematologylibrary.org at PENN STATE UNIVERSITY on February 21, 2013. For personal use only. , 2005 .
[24] Christian Steidl,et al. Essential role of Jun family transcription factors in PU.1 knockdown–induced leukemic stem cells , 2006, Nature Genetics.
[25] Bianca Sperl,et al. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. , 2006, Chemistry & biology.
[26] T. Golub,et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9 , 2006, Nature.
[27] Kenny Q. Ye,et al. Comparative isoschizomer profiling of cytosine methylation: the HELP assay. , 2006, Genome research.
[28] B. Cheson,et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. , 2006, Blood.
[29] I. Weissman,et al. The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[30] Laurie E Ailles,et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. , 2004, The New England journal of medicine.
[31] E. Fikrig,et al. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[32] Irving L. Weissman,et al. Prospective isolation of human clonogenic common myeloid progenitors , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[33] R. DePinho,et al. STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. , 2002, Immunity.
[34] S. E. Jacobsen,et al. Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level. , 2000, Blood.
[35] T Hamblin,et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. , 1997, Blood.