BrainEXP: a database featuring with spatiotemporal expression variations and co‐expression organizations in human brains

Summary: Gene expression changes over the lifespan and varies among different tissues or cell types. Gene co‐expression also changes by sex, age, different tissues or cell types. However, gene expression under the normal state and gene co‐expression in the human brain has not been fully defined and quantified. Here we present a database named Brain EXPression Database (BrainEXP) which provides spatiotemporal expression of individual genes and co‐expression in normal human brains. BrainEXP consists of 4567 samples from 2863 healthy individuals gathered from existing public databases and our own data, in either microarray or RNA‐Seq library types. We mainly provide two analysis results based on the large dataset: (i) basic gene expression across specific brain regions, age ranges and sexes; (ii) co‐expression analysis from different platforms. Availability and implementation: http://www.brainexp.org/ Supplementary information: Supplementary data are available at Bioinformatics online.