Tagetitoxin Inhibits RNA Polymerase through Trapping of the Trigger Loop*
暂无分享,去创建一个
[1] Yulia Yuzenkova,et al. Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre , 2011, Nucleic acids research.
[2] Masaki Yamamoto,et al. Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein , 2010, Nature.
[3] Yulia Yuzenkova,et al. Central role of the RNA polymerase trigger loop in intrinsic RNA hydrolysis , 2010, Proceedings of the National Academy of Sciences.
[4] P. Cramer,et al. Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. , 2009, Molecular cell.
[5] E. Nudler. RNA polymerase active center: the molecular engine of transcription. , 2009, Annual review of biochemistry.
[6] M. Levitt,et al. Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution , 2009, Science.
[7] Wonmuk Hwang,et al. Mechanical Design of Translocating Motor Proteins , 2009, Cell Biochemistry and Biophysics.
[8] E. Nudler,et al. Transcription inactivation through local refolding of the RNA polymerase structure , 2009, Nature.
[9] Jayanta Mukhopadhyay,et al. The RNA Polymerase “Switch Region” Is a Target for Inhibitors , 2008, Cell.
[10] P. Cramer,et al. Structural basis of transcription inhibition by α-amanitin and implications for RNA polymerase II translocation , 2008, Nature Structural &Molecular Biology.
[11] Craig D. Kaplan,et al. The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin. , 2008, Molecular cell.
[12] A. V. Duin,et al. Characterization of the active site of yeast RNA polymerase II by DFT and ReaxFF calculations , 2008 .
[13] E. Nudler,et al. An allosteric path to transcription termination. , 2007, Molecular cell.
[14] Robert Landick,et al. A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing. , 2007, Molecular cell.
[15] Nick V Grishin,et al. Structural basis for converting a general transcription factor into an operon-specific virulence regulator. , 2007, Molecular cell.
[16] Craig D. Kaplan,et al. Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis , 2006, Cell.
[17] Naohiro Matsugaki,et al. Structural basis for transcription inhibition by tagetitoxin , 2005, Nature Structural &Molecular Biology.
[18] T. Tahirov,et al. Structural basis of transcription inhibition by antibiotic streptolydigin. , 2005, Molecular cell.
[19] A. D. Clark,et al. Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation , 2005, Cell.
[20] Arkady Mustaev,et al. A Ratchet Mechanism of Transcription Elongation and Its Control , 2005, Cell.
[21] P. Doruker,et al. Collective Motions of RNA Polymerases. Analysis of Core Enzyme, Elongation Complex and Holoenzyme , 2004, Journal of biomolecular structure & dynamics.
[22] A. Donnenberg,et al. Direct visualization of antigen-specific T cells using peptide-MHC-class I tetrameric complexes. , 2003, Methods.
[23] R. Landick,et al. Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[24] T. Steitz,et al. Structural biology: A mechanism for all polymerases , 1998, Nature.
[25] R. Landick,et al. Termination-altering amino acid substitutions in the beta' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation. , 1994, Genes & development.
[26] C. Gross,et al. Determination of intrinsic transcription termination efficiency by RNA polymerase elongation rate. , 1994, Science.
[27] R. Durbin,et al. Mechanistic aspects of tagetitoxin inhibition of RNA polymerase from Escherichia coli. , 1994, Biochemistry.
[28] T. Steinberg,et al. Tagetitoxin inhibition of RNA polymerase III transcription results from enhanced pausing at discrete sites and is template-dependent. , 1992, Journal of Biological Chemistry.
[29] R. Landick,et al. Amino acid changes in conserved regions of the beta-subunit of Escherichia coli RNA polymerase alter transcription pausing and termination. , 1990, Genes & development.
[30] R. Durbin,et al. Tagetitoxin inhibits RNA synthesis directed by RNA polymerases from chloroplasts and Escherichia coli. , 1990, The Journal of biological chemistry.
[31] C. Yanofsky,et al. Mutations of the beta subunit of RNA polymerase alter both transcription pausing and transcription termination in the trp operon leader region in vitro. , 1983, The Journal of biological chemistry.
[32] Robert Landick,et al. Role of the RNA polymerase trigger loop in catalysis and pausing , 2010, Nature Structural &Molecular Biology.