Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites.
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[1] S. Snyder,et al. HETEROGENEITY OF HISTAMINE Hi‐RECEPTORS: SPECIES VARIATIONS IN [3H]MEPYRAMINE BINDING OF BRAIN MEMBRANES , 1979, Journal of neurochemistry.
[2] D Rodbard,et al. Ligand: a versatile computerized approach for characterization of ligand-binding systems. , 1980, Analytical biochemistry.
[3] S. Hill,et al. HISTAMINE H1‐RECEPTORS IN THE BRAIN OF THE GUINEA‐PIG AND THE RAT: DIFFERENCES IN LIGAND BINDING PROPERTIES AND REGIONAL DISTRIBUTION , 1980, British journal of pharmacology.
[4] R. Lefkowitz,et al. Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. , 1982, Molecular pharmacology.
[5] D. Barnett,et al. [3H]Rauwolscine and [3H]yohimbine binding to rat cerebral and human platelet membranes: possible heterogeneity of alpha 2-adrenoceptors. , 1982, European journal of pharmacology.
[6] R. Summers,et al. The characteristics of adrenoceptors in homogenates of human cerebral cortex labelled by (3H)-rauwolscine. , 1983, Life sciences.
[7] E. Richelson,et al. Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro. , 1984, The Journal of pharmacology and experimental therapeutics.
[8] M. Hamon,et al. [3H]8‐Hydroxy‐2‐(Di‐n‐Propylamino)Tetralin Binding to Pre‐ and Postsynaptic 5‐Hydroxytryptamine Sites in Various Regions of the Rat Brain , 1985, Journal of neurochemistry.
[9] J. Haskins,et al. Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative. , 1986, Biochemical pharmacology.
[10] E. Richelson,et al. Antagonism by antidepressants of serotonin S1 and S2 receptors of normal human brain in vitro. , 1986, European journal of pharmacology.
[11] S. Snyder,et al. Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine. , 1987, The Journal of pharmacology and experimental therapeutics.
[12] J. Saavedra,et al. Chronic treatment with (+/-)DOI, a psychotomimetic 5-HT2 agonist, downregulates 5-HT2 receptors in rat brain. , 1989, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
[13] D. Mckenna. Chronic treatment with (W)DOI, a psychotomimetic 5-HT2 agonist, downregulates 5-HT2 receptors in rat brain , 1989 .
[14] S. Hill,et al. Distribution, properties, and functional characteristics of three classes of histamine receptor. , 1990, Pharmacological reviews.
[15] J. Wess,et al. Antagonist binding profiles of five cloned human muscarinic receptor subtypes. , 1991, The Journal of pharmacology and experimental therapeutics.
[16] C. Nemeroff,et al. The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. II. Biochemical and physiological evidence for the development of tolerance after chronic administration. , 1991, The Journal of pharmacology and experimental therapeutics.
[17] J. Hieble,et al. Structure and function of alpha-adrenoceptors. , 1991, Pharmacological reviews.
[18] G. Duncan,et al. High-performance liquid chromatographic method for the determination of nefazodone and its metabolites in human plasma using laboratory robotics. , 1991, Journal of chromatography.
[19] Randy D. Blakely,et al. Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter , 1991, Nature.
[20] P. Plenge,et al. [3H]Citalopram Binding to Brain and Platelet Membranes of Human and Rat , 1991, Journal of neurochemistry.
[21] S. Tejani-butt. [3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. , 1992, The Journal of pharmacology and experimental therapeutics.
[22] E. Richelson,et al. Antagonism of the five cloned human muscarinic cholinergic receptors expressed in CHO-K1 cells by antidepressants and antihistaminics. , 1993, Biochemical pharmacology.
[23] M. Brann,et al. Studies of the Pharmacology, Localization, and Structure of Muscarinic Acetylcholine Receptors a , 1993, Annals of the New York Academy of Sciences.
[24] E. Richelson,et al. Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes. , 1993, Life sciences.
[25] Heterogeneity of histamine releasing factors and IgE. , 1993, Allergy proceedings : the official journal of regional and state allergy societies.
[26] S. Cheetham,et al. [3H]Paroxetine binding in rat frontal cortex strongly correlates with [3H]5-HT uptake: Effect of administration of various antidepressant treatments , 1993, Neuropharmacology.
[27] S. Hemrick-Luecke,et al. Evaluation of nefazodone as a serotonin uptake inhibitor and a serotonin antagonist in vivo. , 1994, Life sciences.
[28] A. Ontiveros,et al. A double-blind comparison of nefazodone, imipramine, and placebo in major depression. , 1994, The Journal of clinical psychiatry.
[29] R. Blakely,et al. Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands. , 1994, Molecular pharmacology.
[30] C. Clary,et al. Nefazodone and Imipramine in Major Depression: A Placebo-Controlled Trial , 1994, British Journal of Psychiatry.
[31] C. Cole,et al. Characterization of the metabolites of the antidepressant drug nefazodone in human urine and plasma. , 1994, Drug metabolism and disposition: the biological fate of chemicals.
[32] R. B. Carter,et al. Pharmacology and neurochemistry of nefazodone, a novel antidepressant drug. , 1995, The Journal of clinical psychiatry.
[33] R. Blakely,et al. Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants. , 1995, The Journal of experimental biology.
[34] M. Owens,et al. The serotonergic antidepressant nefazodone inhibits the serotonin transporter: in vivo and ex vivo studies. , 1995, Life sciences.
[35] S. Kaul,et al. Nonlinear Pharmacokinetics of Nefazodone After Escalating Single and Multiple Oral Doses , 1995, Journal of clinical pharmacology.
[36] G. Ruigt,et al. The Selective α2-Adrenoceptor Antagonist Mirtazapine (Org 3770) Enhances Noradrenergic and 5-HT1A-Mediated Serotonergic Neurotransmission , 1995 .
[37] D. Archibald,et al. Therapeutic dose range of nefazodone in the treatment of major depression. , 1996, The Journal of clinical psychiatry.
[38] R. Blakely,et al. Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter. , 1996, Molecular pharmacology.
[39] Platelet 5-hydroxytryptamine (5-HT) transporter and 5-HT2A receptor binding after chronic hypercorticosteronemia, (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane administration or neurotoxin-induced depletion of central nervous system 5-HT in the rat. , 1996, The Journal of pharmacology and experimental therapeutics.
[40] J. Heym,et al. Comparison of the Effects of Sertraline and Its Metabolite Desmethylsertraline on Blockade of Central 5-HT Reuptake In Vivo , 1996, Neuropsychopharmacology.
[41] R. Blakely,et al. Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression , 1997, The Journal of Neuroscience.