Epidermal nerve fibers modulate keratinocyte growth via neuropeptide signaling in an innervated skin model.

[1]  M. Schmelz,et al.  Atopic keratinocytes induce increased neurite outgrowth in a coculture model of porcine dorsal root ganglia neurons and human skin cells. , 2012, The Journal of investigative dermatology.

[2]  B. Lüscher,et al.  IL-31 regulates differentiation and filaggrin expression in human organotypic skin models. , 2012, The Journal of allergy and clinical immunology.

[3]  L. Misery,et al.  Effects of the re‐innervation of organotypic skin explants on the epidermis , 2012, Experimental dermatology.

[4]  根木 治 Topically applied semaphorin 3A ointment inhibits scratching behavior and improves skin inflammation in NC/Nga mice with atopic dermatitis , 2012 .

[5]  R. Lavker,et al.  Keratinocyte expression of calcitonin gene-related peptide β: Implications for neuropathic and inflammatory pain mechanisms , 2011, PAIN.

[6]  B. Klapp,et al.  Nerve growth factor partially recovers inflamed skin from stress-induced worsening in allergic inflammation. , 2011, The Journal of investigative dermatology.

[7]  P. Durham,et al.  Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization , 2011, Molecular pain.

[8]  T. Luger,et al.  Itch in atopic dermatitis - pathophysiology and treatment. , 2010, Acta dermatovenerologica Croatica : ADC.

[9]  R. Gallo,et al.  Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8 , 2010, Proceedings of the National Academy of Sciences.

[10]  D. Hay,et al.  Regulation of signal transduction by calcitonin gene-related peptide receptors. , 2010, Trends in pharmacological sciences.

[11]  N. Boulais,et al.  Development of an in vitro coculture of primary sensitive pig neurons and keratinocytes for the study of cutaneous neurogenic inflammation , 2010, Experimental dermatology.

[12]  M. Dusch,et al.  Nerve growth factor‐evoked nociceptor sensitization in pig skin in vivo , 2010, Journal of neuroscience research.

[13]  M. Schmelz,et al.  Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human , 2010, PAIN.

[14]  Chun-Lei Zhou,et al.  Calcitonin gene‐related peptide increases proliferation of human HaCaT keratinocytes by activation of MAP kinases , 2009, Cell biology international.

[15]  K. Matsushima,et al.  Anti‐interleukin‐31‐antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis , 2009, Experimental dermatology.

[16]  M. Caterina,et al.  Overexpressed Transient Receptor Potential Vanilloid 3 Ion Channels in Skin Keratinocytes Modulate Pain Sensitivity via Prostaglandin E2 , 2008, The Journal of Neuroscience.

[17]  S. Hendrix,et al.  Skin and hair follicle innervation in experimental models: a guide for the exact and reproducible evaluation of neuronal plasticity , 2008, Experimental dermatology.

[18]  S. Hunt,et al.  Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice. , 2008, The Journal of investigative dermatology.

[19]  J. Salomon,et al.  The role of selected neuropeptides in pathogenesis of atopic dermatitis , 2007, Journal of the European Academy of Dermatology and Venereology : JEADV.

[20]  B. Klapp,et al.  Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways , 2007, Journal of Molecular Medicine.

[21]  L. Griscom,et al.  In vitro reconstruction of neuro-epidermal connections. , 2007, The Journal of investigative dermatology.

[22]  C. Winborn,et al.  Sensitization of Calcitonin Gene-Related Peptide Receptors by Receptor Activity-Modifying Protein-1 in the Trigeminal Ganglion , 2007, The Journal of Neuroscience.

[23]  Ellen A. Lumpkin,et al.  Mechanisms of sensory transduction in the skin , 2007, Nature.

[24]  C. Griffiths,et al.  The role of neuropeptides in psoriasis , 2006, The British journal of dermatology.

[25]  R. Paus,et al.  Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significance. , 2006, The Journal of investigative dermatology.

[26]  R. Fölster-Holst,et al.  Skin barrier function, epidermal proliferation and differentiation in eczema. , 2006, Journal of dermatological science.

[27]  P. Arck,et al.  Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control , 2006, Experimental dermatology.

[28]  P. Saxena,et al.  Calcitonin gene-related peptide and its role in migraine pathophysiology. , 2004, European journal of pharmacology.

[29]  Scott R. Presnell,et al.  Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice , 2004, Nature Immunology.

[30]  Y. Château,et al.  Connections between nerve endings and epidermal cells: are they synapses? , 2004, Experimental dermatology.

[31]  E. Suuronen,et al.  Innervated human corneal equivalents as in vitro models for nerve‐target cell interactions , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[32]  Sonja Ständer,et al.  Modern aspects of cutaneous neurogenic inflammation. , 2003, Archives of dermatology.

[33]  François Berthod,et al.  In vitro development of a tissue‐engineered model of peripheral nerve regeneration to study neurite growth , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[34]  Z. Ikezawa,et al.  Neuropeptides concentrations in the skin of a murine (NC/Nga mice) model of atopic dermatitis. , 2003, Journal of dermatological science.

[35]  D. Pozo VIP- and PACAP-mediated immunomodulation as prospective therapeutic tools. , 2003, Trends in molecular medicine.

[36]  M. Conconi,et al.  Human skin keratinocytes and fibroblasts express adrenomedullin and its receptors, and adrenomedullin enhances their growth in vitro by stimulating proliferation and inhibiting apoptosis. , 2003, International journal of molecular medicine.

[37]  A. Naukkarinen,et al.  Mast cells, nerves and neuropeptides in atopic dermatitis and nummular eczema , 2003, Archives of Dermatological Research.

[38]  Pietro Cortelli,et al.  Sympathetic skin response: basic mechanisms and clinical applications. , 2003, Clinical autonomic research : official journal of the Clinical Autonomic Research Society.

[39]  Paul H. Black,et al.  Stress and the inflammatory response: A review of neurogenic inflammation , 2002, Brain, Behavior, and Immunity.

[40]  I. Dickerson,et al.  Receptor component protein (RCP): a member of a multi-protein complex required for G-protein-coupled signal transduction. , 2002, Biochemical Society transactions.

[41]  M. Seike,et al.  Increased synthesis of calcitonin gene-related peptide stimulates keratinocyte proliferation in murine UVB-irradiated skin. , 2002, Journal of dermatological science.

[42]  H. Sampson,et al.  Murine model of atopic dermatitis associated with food hypersensitivity. , 2001, The Journal of allergy and clinical immunology.

[43]  N. Fusenig,et al.  Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced keratinocyte growth factor expression in resting fibroblasts. , 2000, The Journal of investigative dermatology.

[44]  S. Hsieh,et al.  Modulation of keratinocyte proliferation by skin innervation. , 1999, The Journal of investigative dermatology.

[45]  Melanie G. Lee,et al.  RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor , 1998, Nature.

[46]  J. McArthur,et al.  Sensory and Motor Denervation Influence Epidermal Thickness in Rat Foot Glabrous Skin , 1997, Experimental Neurology.

[47]  R. Funk,et al.  Immunohistochemical detection of human skin nerve fibers. , 1997, Acta Histochemica.

[48]  M. Green,et al.  The epidermal nerve fibre network: characterization of nerve fibres in human skin by confocal microscopy and assessment of racial variations , 1997, The British journal of dermatology.

[49]  S. Eichmüller,et al.  A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle – dependent changes in mast cell – nerve fiber contacts in murine skin , 1997, Archives of Dermatological Research.

[50]  S. Wimalawansa,et al.  Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily. , 1997, Critical reviews in neurobiology.

[51]  T. Cowen,et al.  Neuropeptides in the skin of patients with atopic dermatitis , 1995, Clinical and experimental dermatology.

[52]  T. Tandrup Are the neurons in the dorsal root ganglion pseudounipolar? A comparison of the number of neurons and number of myelinated and unmyelinated fibres in the dorsal root , 1995, The Journal of comparative neurology.

[53]  G. Wendelschafer‐Crabb,et al.  Keratinocyte muscarinic acetylcholine receptors: immunolocalization and partial characterization. , 1995, The Journal of investigative dermatology.

[54]  M. Rothe Increased Number of Immunoreactive Nerve Fibers in Atopic Dermatitis , 1993 .

[55]  S. Grabbe,et al.  Regulation of Langerhans cell function by nerves containing calcitonin gene-related peptide , 1993, Nature.

[56]  S. Bloom,et al.  Differential expression of α-CGRP and β-CGRP by primary sensory neurons and enteric autonomic neurons of the rat , 1988, Neuroscience.

[57]  K. Danno,et al.  Effects of substance P and substance K on the growth of cultured keratinocytes. , 1988, The Journal of investigative dermatology.

[58]  S. Amara,et al.  Differential expression of alpha-CGRP and beta-CGRP by primary sensory neurons and enteric autonomic neurons of the rat. , 1988, Neuroscience.

[59]  B. Coventry,et al.  Two immunohistochemically identified populations of calcitonin gene-related peptide (CGRP)-immunoreactive axons in human skin , 1987, Brain Research.

[60]  D. Regoli,et al.  Pharmacological receptors for substance P and neurokinins. , 1987, Life sciences.

[61]  C. Martyn,et al.  Sympathetic skin response. , 1985, Journal of neurology, neurosurgery, and psychiatry.

[62]  V. Erspamer The tachykinin peptide family , 1981, Trends in Neurosciences.

[63]  U Kiistala,et al.  Suction blister device for separation of viable epidermis from dermis. , 1968, The Journal of investigative dermatology.