Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues.

[1]  J. Hartman,et al.  Slowing ribosome velocity restores folding and function of mutant CFTR. , 2019, The Journal of clinical investigation.

[2]  E. Sorscher,et al.  Making precision medicine personal for cystic fibrosis , 2019, Science.

[3]  P. Carmeliet,et al.  Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR , 2019, Cell.

[4]  E. Hoffman,et al.  Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR‐Knockout Ferrets , 2018, American journal of respiratory and critical care medicine.

[5]  S. Wenzel,et al.  ATP12A promotes mucus dysfunction during Type 2 airway inflammation , 2018, Scientific Reports.

[6]  Z. Ignatova,et al.  Alteration of protein function by a silent polymorphism linked to tRNA abundance , 2017, PLoS biology.

[7]  R. Gibson,et al.  Molecular Genetics of Cystic Fibrosis Transmembrane Conductance Regulator: Genotype and Phenotype. , 2016, Pediatric clinics of North America.

[8]  Yi-Wen Chen,et al.  Effects on muscle tissue remodeling and lipid metabolism in muscle tissue from adult patients with polymyositis or dermatomyositis treated with immunosuppressive agents , 2016, Arthritis Research & Therapy.

[9]  R. Aebersold,et al.  On the Dependency of Cellular Protein Levels on mRNA Abundance , 2016, Cell.

[10]  Z. Ignatova,et al.  Tuning innate immunity by translation. , 2015, Biochemical Society transactions.

[11]  M. Konstan,et al.  Inflammation in cystic fibrosis lung disease: Pathogenesis and therapy. , 2015, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[12]  Garry R. Cutting,et al.  Cystic fibrosis genetics: from molecular understanding to clinical application , 2014, Nature Reviews Genetics.

[13]  J. Karp,et al.  Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny , 2013, Nature Methods.

[14]  Hiroyuki Miyoshi,et al.  In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture , 2013, Nature Protocols.

[15]  A. Fullaondo,et al.  E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes , 2013, Nucleic acids research.

[16]  E. Kerem,et al.  Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications , 2013, Thorax.

[17]  Peter D Sly,et al.  Risk factors for bronchiectasis in children with cystic fibrosis. , 2013, The New England journal of medicine.

[18]  R. Kaufman,et al.  ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death , 2013, Nature Cell Biology.

[19]  E. Marcotte,et al.  Insights into the regulation of protein abundance from proteomic and transcriptomic analyses , 2012, Nature Reviews Genetics.

[20]  Hans Clevers,et al.  Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. , 2011, Gastroenterology.

[21]  M. Selbach,et al.  Global quantification of mammalian gene expression control , 2011, Nature.

[22]  A. Zhu,et al.  The role of signaling pathways in the development and treatment of hepatocellular carcinoma , 2010, Oncogene.

[23]  J. Freyssinet,et al.  Mechanisms of the noxious inflammatory cycle in cystic fibrosis , 2009, Respiratory research.

[24]  B. Williams,et al.  Mapping and quantifying mammalian transcriptomes by RNA-Seq , 2008, Nature Methods.

[25]  J. Wakefield,et al.  Activation of the unfolded protein response by deltaF508 CFTR. , 2008, American journal of respiratory cell and molecular biology.

[26]  R. Kaufman,et al.  ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress. , 2007, Developmental cell.

[27]  P. Walter,et al.  Signal integration in the endoplasmic reticulum unfolded protein response , 2007, Nature Reviews Molecular Cell Biology.

[28]  A. Nicholson,et al.  Airway remodelling in children with cystic fibrosis , 2007, Thorax.

[29]  J. Wakefield,et al.  Endoplasmic reticulum stress and the unfolded protein response regulate genomic cystic fibrosis transmembrane conductance regulator expression. , 2007, American journal of physiology. Cell physiology.

[30]  J. Wakefield,et al.  Failure of cAMP agonists to activate rescued ΔF508 CFTR in CFBE41o– airway epithelial monolayers , 2005, The Journal of physiology.

[31]  L. Glimcher,et al.  XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response , 2003, Molecular and Cellular Biology.

[32]  W. Colledge,et al.  ΔF508-CFTR Causes Constitutive NF-κB Activation through an ER-Overload Response in Cystic Fibrosis Lungs , 2002 .

[33]  H. Pahl Activators and target genes of Rel/NF-κB transcription factors , 1999, Oncogene.

[34]  Melvin Berger,et al.  Current understanding of the inflammatory process in cystic fibrosis: Onset and etiology , 1997, Pediatric pulmonology.

[35]  S. Randell,et al.  Primary epithelial cell models for cystic fibrosis research. , 2011, Methods in molecular biology.

[36]  P. Jeffery Inflammation and remodeling in the adult and child with asthma , 2001, Pediatric pulmonology. Supplement.