Respiratory Motion Correction in Abdominal MRI using a Densely Connected U-Net with GAN-guided Training

Abdominal magnetic resonance imaging (MRI) provides a straightforward way of characterizing tissue and locating lesions of patients as in standard diagnosis. However, abdominal MRI often suffers from respiratory motion artifacts, which leads to blurring and ghosting that significantly deteriorate the imaging quality. Conventional methods to reduce or eliminate these motion artifacts include breath holding, patient sedation, respiratory gating, and image post-processing, but these strategies inevitably involve extra scanning time and patient discomfort. In this paper, we propose a novel deep-learning-based model to recover MR images from respiratory motion artifacts. The proposed model comprises a densely connected U-net with generative adversarial network (GAN)-guided training and a perceptual loss function. We validate the model using a diverse collection of MRI data that are adversely affected by both synthetic and authentic respiration artifacts. Effective outcomes of motion removal are demonstrated. Our experimental results show the great potential of utilizing deep-learning-based methods in respiratory motion correction for abdominal MRI.

[1]  Bernhard Schölkopf,et al.  Blind retrospective motion correction of MR images , 2012, Magnetic resonance in medicine.

[2]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[3]  Jimmy Ba,et al.  Adam: A Method for Stochastic Optimization , 2014, ICLR.

[4]  Chi-Wing Fu,et al.  H-DenseUNet: Hybrid Densely Connected UNet for Liver and Tumor Segmentation From CT Volumes , 2018, IEEE Transactions on Medical Imaging.

[5]  H. Hricak,et al.  Magnetic resonance imaging with respiratory gating: techniques and advantages. , 1984, AJR. American journal of roentgenology.

[6]  Christian Ledig,et al.  Photo-Realistic Single Image Super-Resolution Using a Generative Adversarial Network , 2016, 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[7]  M. Zaitsev,et al.  Motion artifacts in MRI: A complex problem with many partial solutions , 2015, Journal of magnetic resonance imaging : JMRI.

[8]  Michael Lustig,et al.  Clinical performance of contrast enhanced abdominal pediatric MRI with fast combined parallel imaging compressed sensing reconstruction , 2014, Journal of magnetic resonance imaging : JMRI.

[9]  P. Mansfield Multi-planar image formation using NMR spin echoes , 1977 .

[10]  T. Voepel-Lewis,et al.  Sedation and general anaesthesia in children undergoing MRI and CT: adverse events and outcomes. , 2000, British journal of anaesthesia.

[11]  Alexei A. Efros,et al.  Image-to-Image Translation with Conditional Adversarial Networks , 2016, 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[12]  Daiki Tamada,et al.  Motion Artifact Reduction Using a Convolutional Neural Network for Dynamic Contrast Enhanced MR Imaging of the Liver , 2018, Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.

[13]  D. Donoho,et al.  Sparse MRI: The application of compressed sensing for rapid MR imaging , 2007, Magnetic resonance in medicine.

[14]  Sergios Gatidis,et al.  Retrospective Correction Of Rigid And Non-Rigid MR Motion Artifacts Using Gans , 2018, 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019).