Title: Multidimensional extracellular-matrix analysis reveals a silent pre-clinical signature in inflammatory disease

Affiliations: Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel 10 Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel CIMAINA and Department of Physics, Università degli Studi di Milano, Milano, Italy CERM and Department of Chemistry, University of Florence, Italy Research Center for Digestive Tract and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel 15 Pediatric Gastroenterology Unit, Edmond and Lily Safra Children’s Hospital, Sheba Medical Center, Tel Hashomer, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel

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