Sequence, Structure, and Network Evolution of Protein Phosphorylation

Analysis of phosphorylation-based signaling systems provides insight into the evolution of these regulatory molecules. With the increasing amount of information about the phosphoproteomes of diverse organisms, it is now possible to begin to evaluate this information in the context of evolution. Work described at the inaugural Keystone Symposium on “The Evolution of Protein Phosphorylation” covered a wide range of eukaryotic and prokaryotic organisms, revealing insights into the evolution of protein phosphorylation at the sequence, network, and structural levels.

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