High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism
暂无分享,去创建一个
Thomas R. Ioerger | Michael A. DeJesus | Christopher M. Sassetti | T. Ioerger | C. Sassetti | Jennifer E. Griffin | Jeffrey D. Gawronski | M. DeJesus | B. Akerley | Brian J. Akerley
[1] Jay Shendure,et al. Genome-Scale Identification of Resistance Functions in Pseudomonas aeruginosa Using Tn-seq , 2011, mBio.
[2] J. Mekalanos,et al. In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[3] E. Rubin,et al. Comprehensive identification of conditionally essential genes in mycobacteria , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[4] Georgia Giannoukos,et al. Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung , 2009, Proceedings of the National Academy of Sciences.
[5] I. Smith,et al. Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. , 2009, Biochemistry.
[6] Carolyn R Bertozzi,et al. MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[7] S. Fortune,et al. Characterization of mycobacterial virulence genes through genetic interaction mapping. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[8] Stefan Niemann,et al. Mycobacterium tuberculosis wears what it eats. , 2010, Cell host & microbe.
[9] Gary K. Schoolnik,et al. ideR, an Essential Gene in Mycobacterium tuberculosis: Role of IdeR in Iron-Dependent Gene Expression, Iron Metabolism, and Oxidative Stress Response , 2002, Infection and Immunity.
[10] Eric Haugen,et al. Comprehensive transposon mutant library of Pseudomonas aeruginosa , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[11] V. Mizrahi,et al. The Stringent Response of Mycobacterium tuberculosis Is Required for Long-Term Survival , 2000, Journal of bacteriology.
[12] A. Camilli,et al. Tn-seq; high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms , 2009, Nature Methods.
[13] J. Mekalanos,et al. Systematic identification of essential genes by in vitro mariner mutagenesis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[14] Irina Kolesnikova,et al. A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol , 2009, Infection and Immunity.
[15] Jonathan B. Johnston,et al. Functional Redundancy of Steroid C26-monooxygenase Activity in Mycobacterium tuberculosis Revealed by Biochemical and Genetic Analyses* , 2010, The Journal of Biological Chemistry.
[16] S. Guan,et al. Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest‐4‐en‐3‐one , 2010, Molecular microbiology.
[17] M. Benziman,et al. Pyruvate-phosphate dikinase and the control of gluconeogenesis in Acetobacter xylinum. , 1971, The Journal of biological chemistry.
[18] L. Dijkhuizen,et al. A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages , 2007, Proceedings of the National Academy of Sciences.
[19] J. Shendure,et al. Selection analyses of insertional mutants using subgenic-resolution arrays , 2001, Nature Biotechnology.
[20] O. White,et al. Global transposon mutagenesis and a minimal Mycoplasma genome. , 1999, Science.
[21] E. Muñoz-Elías,et al. Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence , 2005, Nature Medicine.
[22] R. Geffers,et al. Role of the Transcriptional Regulator RamB (Rv0465c) in the Control of the Glyoxylate Cycle in Mycobacterium tuberculosis , 2009, Journal of bacteriology.
[23] W. Jacobs,et al. Two Nonredundant SecA Homologues Function in Mycobacteria , 2001, Journal of bacteriology.
[24] L. Dijkhuizen,et al. Cytochrome P450 125 (CYP125) catalyses C26‐hydroxylation to initiate sterol side‐chain degradation in Rhodococcus jostii RHA1 , 2009, Molecular microbiology.
[25] J. Mckinney,et al. Role of KatG catalase‐peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst , 2004, Molecular microbiology.
[26] James C Sacchettini,et al. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis , 2006, Molecular microbiology.
[27] I. Smith,et al. Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase. , 2007, Biochemistry.
[28] B. Barrell,et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence , 1998, Nature.
[29] M. Osteras,et al. Increased pyruvate orthophosphate dikinase activity results in an alternative gluconeogenic pathway in Rhizobium (Sinorhizobium) meliloti. , 1997, Microbiology.
[30] James C. Sacchettini,et al. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase , 2000, Nature.
[31] Rob Knight,et al. Identifying genetic determinants needed to establish a human gut symbiont in its habitat. , 2009, Cell host & microbe.
[32] Christopher M. Sassetti,et al. Genetic requirements for mycobacterial survival during infection , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[33] Karl W. Broman,et al. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: Application to Mycobacterium tuberculosis , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[34] M. Churchill,et al. A purified mariner transposase is sufficient to mediate transposition in vitro , 1996, The EMBO journal.
[35] J. Dziadek,et al. Cholesterol oxidase is required for virulence of Mycobacterium tuberculosis. , 2007, FEMS microbiology letters.
[36] W. Jacobs,et al. Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis , 2009, PLoS pathogens.
[37] E. Rubin,et al. Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[38] Christopher M. Sassetti,et al. Mycobacterial persistence requires the utilization of host cholesterol , 2008, Proceedings of the National Academy of Sciences.
[39] Christopher M. Sassetti,et al. igr Genes and Mycobacterium tuberculosis Cholesterol Metabolism , 2009, Journal of bacteriology.
[40] G. Besra,et al. Mycobacterium tuberculosis pks12 Produces a Novel Polyketide Presented by CD1c to T Cells , 2004, The Journal of experimental medicine.
[41] Leopold Parts,et al. Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants. , 2009, Genome research.
[42] W. Jacobs,et al. Mycobacterial Cytochrome P450 125 (Cyp125) Catalyzes the Terminal Hydroxylation of C27 Steroids* , 2009, The Journal of Biological Chemistry.
[43] I. Smith,et al. Cholesterol Is Not an Essential Source of Nutrition for Mycobacterium tuberculosis during Infection , 2011, Journal of bacteriology.
[44] E. Rubin,et al. Genes required for mycobacterial growth defined by high density mutagenesis , 2003, Molecular microbiology.
[45] Ruiqiang Li,et al. SOAP: short oligonucleotide alignment program , 2008, Bioinform..
[46] Sabine Ehrt,et al. Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection , 2010, Proceedings of the National Academy of Sciences.
[47] Mahavir Singh,et al. 3‐Ketosteroid 9α‐hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis , 2010, Molecular microbiology.