Structure of a biologically active estrogen receptor-coactivator complex on DNA.
暂无分享,去创建一个
W. Chiu | S. Ludtke | R. Lanz | B. O’Malley | M. Schmid | C. Foulds | G. Pintilie | P. Yi | Zhao Wang | Q. Feng
[1] B. O’Malley,et al. Nuclear receptor modulation – Role of coregulators in selective estrogen receptor modulator (SERM) actions , 2014, Steroids.
[2] J. Schwabe,et al. An evolving understanding of nuclear receptor coregulator proteins. , 2013, Journal of molecular endocrinology.
[3] Ross A. Hamilton,et al. Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics. , 2013, Molecular cell.
[4] W. Chiu,et al. Visualizing GroEL/ES in the Act of Encapsulating a Folding Protein , 2013, Cell.
[5] W. Chiu,et al. Validation of cryo-EM structure of IP₃R1 channel. , 2013, Structure.
[6] Dalei Wu,et al. Multi-Domain Integration in the Structure of the HNF4α Nuclear Receptor Complex , 2013, Nature.
[7] S. Scheres. RELION: Implementation of a Bayesian approach to cryo-EM structure determination , 2012, Journal of structural biology.
[8] W. Chiu,et al. Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in cryo-EM density maps. , 2012, Biopolymers.
[9] Shaoxia Chen,et al. Prevention of overfitting in cryo-EM structure determination , 2012, Nature Methods.
[10] D. Moras,et al. Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors , 2012, Proceedings of the National Academy of Sciences.
[11] M. Baker,et al. Outcome of the First Electron Microscopy Validation Task Force Meeting , 2012, Structure.
[12] D. Moras,et al. Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA , 2012, The EMBO journal.
[13] V. Theodorou,et al. Oestrogen receptor–co‐factor–chromatin specificity in the transcriptional regulation of breast cancer , 2011, The EMBO journal.
[14] Richard Henderson,et al. Tilt-Pair Analysis of Images from a Range of Different Specimens in Single-Particle Electron Cryomicroscopy , 2011, Journal of molecular biology.
[15] A. Malovannaya,et al. Global characterization of transcriptional impact of the SRC-3 coregulator. , 2010, Molecular endocrinology.
[16] Petra C. Schwalie,et al. A CTCF-independent role for cohesin in tissue-specific transcription. , 2010, Genome research.
[17] Y. Hamuro,et al. Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA , 2008, Nature.
[18] D. Moras,et al. Monitoring ligand modulation of protein-protein interactions by mass spectrometry: estrogen receptor alpha-SRC1. , 2008, Analytical chemistry.
[19] M. Baker,et al. Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel , 2008, Proceedings of the National Academy of Sciences.
[20] B. O’Malley,et al. Signaling within a Coactivator Complex: Methylation of SRC-3/AIB1 Is a MolecularSwitch for Complex Disassembly , 2006, Molecular and Cellular Biology.
[21] Janice Bramham,et al. Structural Diversity in p160/CREB-binding Protein Coactivator Complexes* , 2006, Journal of Biological Chemistry.
[22] J. Frank,et al. A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation. , 2006, Journal of structural biology.
[23] Clifford A. Meyer,et al. Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1 , 2005, Cell.
[24] W. Shao,et al. Coactivator AIB1 links estrogen receptor transcriptional activity and stability. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[25] Y. Shang,et al. Differential gene regulation by the SRC family of coactivators. , 2004, Genes & development.
[26] Heike Brand,et al. Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter , 2003, Cell.
[27] R. Henderson,et al. Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy. , 2003, Journal of molecular biology.
[28] J. Gustafsson,et al. Activation functions 1 and 2 of nuclear receptors: molecular strategies for transcriptional activation. , 2003, Molecular endocrinology.
[29] Carolyn L. Smith,et al. Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains. , 2003, Molecular endocrinology.
[30] M. Ikeda,et al. Growth suppression of human carcinoma cells by reintroduction of the p300 coactivator , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[31] Wei Xu,et al. Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators , 2002, Nature.
[32] R. Métivier,et al. Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains. , 2001, Molecular endocrinology.
[33] N. L. La Thangue,et al. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. , 2001, Journal of cell science.
[34] C. Powers,et al. Ribozyme Targeting Demonstrates That the Nuclear Receptor Coactivator AIB1 Is a Rate-limiting Factor for Estrogen-dependent Growth of Human MCF-7 Breast Cancer Cells* , 2001, The Journal of Biological Chemistry.
[35] J. T. Kadonaga,et al. p300 Forms a Stable, Template-Committed Complex with Chromatin: Role for the Bromodomain , 2001, Molecular and Cellular Biology.
[36] E. Gratton,et al. The human estrogen receptor alpha dimer binds a single SRC-1 coactivator molecule with an affinity dictated by agonist structure. , 2001, Journal of molecular biology.
[37] S. Na,et al. Transcriptional coregulators of the nuclear receptor superfamily: coactivators and corepressors , 2001, Cellular and Molecular Life Sciences CMLS.
[38] Myles Brown,et al. Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription , 2000, Cell.
[39] R. Goodman,et al. CBP/p300 in cell growth, transformation, and development. , 2000, Genes & development.
[40] J. Wong,et al. p300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin , 2000, Molecular and Cellular Biology.
[41] J. T. Kadonaga,et al. Biochemical Analysis of Distinct Activation Functions in p300 That Enhance Transcription Initiation with Chromatin Templates , 1999, Molecular and Cellular Biology.
[42] B. Katzenellenbogen,et al. Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor. , 1999, Molecular endocrinology.
[43] David A. Agard,et al. The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen , 1998, Cell.
[44] T. Willson,et al. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ , 1998, Nature.
[45] D. Edwards,et al. The Steroid Receptor Coactivator-1 Contains Multiple Receptor Interacting and Activation Domains That Cooperatively Enhance the Activation Function 1 (AF1) and AF2 Domains of Steroid Receptors* , 1998, The Journal of Biological Chemistry.
[46] J. T. Kadonaga,et al. p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation. , 1998, Genes & development.
[47] Zbigniew Dauter,et al. Molecular basis of agonism and antagonism in the oestrogen receptor , 1997, Nature.
[48] David M. Heery,et al. A signature motif in transcriptional co-activators mediates binding to nuclear receptors , 1997, Nature.
[49] Christopher K. Glass,et al. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function , 1997, Nature.
[50] J. Direnzo,et al. p300 is a component of an estrogen receptor coactivator complex. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[51] Thorsten Heinzel,et al. A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors , 1996, Cell.
[52] J. Dubochet,et al. Cryo-electron microscopy of vitrified specimens , 1988, Quarterly Reviews of Biophysics.
[53] Wen Jiang,et al. EMAN2: an extensible image processing suite for electron microscopy. , 2007, Journal of structural biology.