Special Issue on Multiscale Modeling in Biology

This special issue of Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal, on multiscale modeling in biology, stems from the workshop "Biocomplexity V: Multiscale Modeling in Biology," held August 14--17, 2003, at the University of Notre Dame and organized jointly by the Interdisciplinary Center for the Study of Biocomplexity at the University of Notre Dame, the Biocomplexity Institute at Indiana University, and Los Alamos National Laboratory, in cooperation with the Society for Industrial and Applied Mathematics. The workshop took place in conjunction with the Notre Dame Conference on Partial Differential Equations with Applications. Modeling and simulation are becoming central research tools in biology. The most advanced of these efforts have focused on single levels or scales, e.g., genomic/proteomic, cellular, tissue, organ, whole body, behavioral, and population. We now need to develop the software tools and mathematical approaches to integrate models from micro-scales to macro-scale...