Matrix Metalloproteinase-1 Expression in Fibroblasts Accelerates Dermal Aging and Promotes Papilloma Development in Mouse Skin.

[1]  P. Janmey,et al.  Effects of extracellular matrix viscoelasticity on cellular behaviour , 2020, Nature.

[2]  A. Weeraratna,et al.  How the ageing microenvironment influences tumour progression , 2019, Nature Reviews Cancer.

[3]  A. Dufour,et al.  Matrix Metalloproteases as Influencers of the Cells’ Social Media , 2019, International journal of molecular sciences.

[4]  T. Quan,et al.  Age‐related reduction of dermal fibroblast size upregulates multiple matrix metalloproteinases as observed in aged human skin in vivo , 2017, The British journal of dermatology.

[5]  D. Gullberg,et al.  The integrin–collagen connection – a glue for tissue repair? , 2016, Journal of Cell Science.

[6]  J. Voorhees,et al.  Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging , 2015, Aging cell.

[7]  S. Feldman,et al.  Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012. , 2015, JAMA dermatology.

[8]  M. Stratton,et al.  High burden and pervasive positive selection of somatic mutations in normal human skin , 2015, Science.

[9]  J. Voorhees,et al.  A mouse model of skin aging: fragmentation of dermal collagen fibrils and reduced fibroblast spreading due to expression of human matrix metalloproteinase-1. , 2015, Journal of dermatological science.

[10]  T. Quan,et al.  Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review , 2015, Gerontology.

[11]  A. Lehmann,et al.  TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin , 2015, Proceedings of the National Academy of Sciences.

[12]  M. Sheetz,et al.  Appreciating force and shape — the rise of mechanotransduction in cell biology , 2014, Nature Reviews Molecular Cell Biology.

[13]  Jay D. Humphrey,et al.  Mechanotransduction and extracellular matrix homeostasis , 2014, Nature Reviews Molecular Cell Biology.

[14]  M. Imperiale,et al.  Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice , 2014, The Journal of investigative dermatology.

[15]  J. Voorhees,et al.  Age-associated reduction of cellular spreading/mechanical force up-regulates matrix metalloproteinase-1 expression and collagen fibril fragmentation via c-Jun/AP-1 in human dermal fibroblasts , 2014, Aging cell.

[16]  D. Ingber,et al.  Mechanobiology and developmental control. , 2013, Annual review of cell and developmental biology.

[17]  J. Voorhees,et al.  Expression of catalytically active matrix metalloproteinase‐1 in dermal fibroblasts induces collagen fragmentation and functional alterations that resemble aged human skin , 2013, Aging cell.

[18]  A. Dufour,et al.  Missing the target: matrix metalloproteinase antitargets in inflammation and cancer. , 2013, Trends in pharmacological sciences.

[19]  J. Voorhees,et al.  Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells and keratinocytes in aged human skin in vivo , 2012, The Journal of investigative dermatology.

[20]  J. Voorhees,et al.  CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts , 2011, Journal of Cell Communication and Signaling.

[21]  R. Bischoff,et al.  Physiology and pathophysiology of matrix metalloproteases , 2010, Amino Acids.

[22]  B. de Crombrugghe,et al.  Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. , 2010, Arthritis and rheumatism.

[23]  Z. Werb,et al.  Matrix Metalloproteinases: Regulators of the Tumor Microenvironment , 2010, Cell.

[24]  K. Kiguchi,et al.  Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications , 2009, Nature Protocols.

[25]  Hyojin Cho,et al.  Additional MDA‐MB‐231 breast cancer cell matrix metalloproteinases promote invasiveness , 2008, Journal of cellular physiology.

[26]  James Varani,et al.  Looking older: fibroblast collapse and therapeutic implications. , 2008, Archives of dermatology.

[27]  L. Luo,et al.  A global double‐fluorescent Cre reporter mouse , 2007, Genesis.

[28]  Andrew J. Ewald,et al.  Matrix metalloproteinases and the regulation of tissue remodelling , 2007, Nature Reviews Molecular Cell Biology.

[29]  M. Hebrok,et al.  Hedgehog/Ras interactions regulate early stages of pancreatic cancer. , 2006, Genes & Development.

[30]  William C. Parks,et al.  Matrix metalloproteinases as modulators of inflammation and innate immunity , 2004, Nature Reviews Immunology.

[31]  E. Wagner,et al.  AP-1: a double-edged sword in tumorigenesis , 2003, Nature Reviews Cancer.

[32]  J. Voorhees,et al.  Matrix Metalloproteinase-1 is the Major Collagenolytic Enzyme Responsible for Collagen Damage in UV-irradiated Human Skin¶ , 2003 .

[33]  J. Voorhees,et al.  Pathophysiology of premature skin aging induced by ultraviolet light. , 1997, The New England journal of medicine.

[34]  C. S. Chen,et al.  Geometric control of cell life and death. , 1997, Science.

[35]  R. Tarone,et al.  Frequent clones of p53-mutated keratinocytes in normal human skin. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[36]  J. Voorhees,et al.  Molecular basis of sun-induced premature skin ageing and retinoid antagonism , 1996, Nature.

[37]  Y. Okada,et al.  Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis , 1995, Molecular and cellular biology.

[38]  George Bou-Gharios,et al.  Characterization of Mesenchymal-Fibroblast Cells Using the Col1a2 Promoter/Enhancer. , 2017, Methods in molecular biology.

[39]  A. Wells,et al.  Skin tissue repair: Matrix microenvironmental influences. , 2016, Matrix biology : journal of the International Society for Matrix Biology.

[40]  J. DiGiovanni,et al.  Multistage carcinogenesis in mouse skin. , 1992, Pharmacology & therapeutics.

[41]  J. Voorhees,et al.  Epithelial and Mesenchymal Cell Biology Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin Address Reprint Requests To , 2022 .